212324-23-7Relevant academic research and scientific papers
(E)-and (Z)-3-(4-chloro-5H-dithiazol-5-ylidene)-1,1,1-trifluoropentane- 2,4-diones and their analogs: Stereochemistry and their mechanisms of formation
Lee, Hyi-Seung,Kim, Kyongtae
, p. 5781 - 5784 (1998)
The reactions of Appel's salt with active methylene compounds such as 1,1,1,5,5,5-hexafluoro-2,4-pentanedione, 1,1,1-trifluoro-2,4-pentanedione, ethyl 4,4,4-trifluoro-3-oxobutanoate, 4,4,4-trifluoro-1-phenyl-1,3- butanedione, and 4,4,4-trifluoro-1-(2-naph
Synthesis of new 5-alkylidene-4-chloro-5h-1,2,3-dithiazoles and their stereochemistry
Jeon, Moon-Kook,Kyongtae, Kim
, p. 9651 - 9667 (1999)
A variety of 5-alkylidene-4-chloro-5H-1,2,3-dithiazoles (9-25) have been prepared from 4-chloro-5H-1,2,3-dithiazolium chloride, active methylene compounds, and pyridine. The reactions with ethyl nitroacetate ((Z) > (E)), ethyl 3-nitrobenzoylacetate ((E) > (Z)), ethyl 2-fluorobenzoylacetate ((E) > (Z)), and tetronic acid ((Z) > (E)) gave a mixture of (E)- and (Z)-isomers, whereas those of benzoylnitromethane (Z), 5,6-dihydro-4-hydroxy-6-methyl-2H- pyran-2-one (E), 4-hydroxy-6-methyl-2-pyrone (E), 4-hydroxycoumarin (E), 6- chloro-4-hydroxycoumarin (E), and 6-bromo-4-hydroxycoumarin (E) afforded only single stereoisomers. The reactions with 4-hydroxy-1-methyl-2(IH)-quinolone, 2-hydroxy-1,4-naphthoquinone and homophthalic anhydride gave only single stereoisomers whose stereochemistry is uncertain. It appears that geometrically more rigid cyclic 1,3-dicarbonyl compounds give better yields of dithiazol-5-ylidenes than the corresponding acyclic compounds.
