21239-87-2

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 9 carbon atoms, 8 hydrogen atoms, 4 nitrogen atoms, and 1 sulfur atom.

Explanation

This structure indicates that the compound is a triazole derivative with a phenylmethylthio group attached to the third carbon of the triazole ring.

Explanation

The compound is derived from the triazole ring, which is a five-membered ring containing three nitrogen atoms and two carbon atoms.

Explanation

The phenylmethylthio group is a functional group consisting of a phenyl ring attached to a methyl group, which is further connected to a sulfur atom.

Explanation

The compound is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It also exhibits biological activity and has been studied for its potential as an anti-cancer and anti-inflammatory agent. Additionally, it has shown potential as a corrosion inhibitor and as a ligand in coordination chemistry.

Explanation

The compound has been found to have biological activity, which means it can interact with living organisms and potentially produce an effect or response.

Explanation

Research has been conducted to explore the compound's potential as an anti-cancer agent, which could lead to the development of new cancer treatments.

Explanation

The compound has also been studied for its potential as an anti-inflammatory agent, which could be useful in the development of new treatments for inflammatory conditions.

Explanation

The compound has demonstrated potential as a corrosion inhibitor, which could be applied in various industries to protect materials from corrosion.

Explanation

The compound has shown potential as a ligand in coordination chemistry, which could be used to form complexes with metal ions and study their properties and applications.

Chemical Structure

1H-1,2,4-Triazole, 3-[(phenylmethyl)thio]-

Triazole Derivative

Yes

Phenylmethylthio Group

Attached to the third carbon of the triazole ring

Applications

Pharmaceutical and agrochemical synthesis, anti-cancer and anti-inflammatory agent, corrosion inhibitor, and coordination chemistry ligand

Biological Activity

Exhibited

Potential as an Anti-cancer Agent

Studied

Potential as an Anti-inflammatory Agent

Studied

Corrosion Inhibition

Shown potential

Coordination Chemistry Ligand

Shown potential

Upstream product

• 100-44-7 benzyl chloride 
• 3179-31-5 1H-1,2,4-triazole-5-thiol 
• 100-39-0 benzyl bromide 
• 3179-31-5 1H-[1,2,4]triazole-3-thiol 
• 39751-89-8 potassium 5-mercapto-1,3,4-triazole 
• 3179-31-5 3-mercapto-1,2,4-triazole 

Downstream Products

• 475588-40-0 3-benzylthio-1-dimethylcarbamoyl-1H-1,2,4-triazole 
• 120288-41-7 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-3-benzylthio-1,2,4-triazole 
• 120288-43-9 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-5-benzylthio-1,2,4-triazole 
• 120288-44-0 1-β-D-Ribofuranosyl-5-benzylthio-1,2,4-triazole 
• 120288-42-8 1-β-D-Ribofuranosyl-3-benzylthio-1,2,4-triazole 
• 29982-79-4 5-Phenylmethanesulfonyl-1H-[1,2,4]triazole 
• 29982-78-3 5-Phenylmethanesulfinyl-1H-[1,2,4]triazole 

Relevant academic research and scientific papers

Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials

(Graph Presented) Screening of the GSK corporate collection, some 1.9 million compounds, against Plasmodium falciparum (Pf), revealed almost 14000 active hits that are now known as the Tres Cantos Antimalarial Set (TCAMS). Followup work by Calderon et al.

Synthesis of novel 1, 3-Substituted 1 H-[1, 2, 4]-Triazole-3-Thiol derivatives

By means of regioselective S-alkylation of 1 H-1, 2, 4-triazole-3-thiol (1), a series of S-substituted derivatives 2a-j were synthesized. In certain conditions, the reaction of 2 with arylsul-fochlorides, arylisocyanates, and quaternary ammonium salts of

Synthesis and antimycobacterial activity of 1,2,4-triazole 3-benzylsulfanyl derivatives

Series of 3-benzylsulfanyl derivatives of 1,2,4-triazole and 4-methyl-1,2,4-triazole were synthesized by alkylation of starting triazole-3-thiol with appropriately substituted benzyl halide. All members of the set were evaluated for in vitro antimycobacte

Pharmaceutical use of N-Carbamoylazole derivatives

The present invention relates to use of 1-carbamoylazole derivatives as medicaments and pharmaceutical compositions containing 1-carbamoylazole derivatives as the active ingredient, based on their DPPIV inhibiting effects. The present invention provides a dipeptidyl peptidase IV inhibiting agent comprising a compound represented by the general formula (I):

A Unified Approach to Systematic Isoesteric Substitution for Acidic Groups and Application to NMDA Antagonists Related to 2-Amino-7-phosphonoheptanoate

A systematic approach to the replacement of acidic groups with potential bioisoesteres is described.The strategy involves simple nucleophilic displacement of a common alkyl halide precursor with a variety of mercaptoazoles and related molecules.The mercaptoazoles and their oxidized derivatives (sulfinyl- and sulfonylazoles) represent a series of possible surrogates for acidic groups which span a pKa range from about 4.5-11.5.This simple strategy was extended to include 2-hydroxy- or 2-aminothiophenyl groups which function as relatively nonacidic isoesteres for a phosphonic acid.By replacing the phosphonic acid of 2-amino-7-phosphonoheptanoate (AP-7) with these groups, we have synthesized novel N-methyl-d-aspartate (NMDA) antagonists.

Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide

The novel compound having the structural formula STR1 is disclosed, as well as its use by pre-emergent application to control noxious grasses and some broadleaf weeds in cool season crops such as rape, sugar beets and flax.