212487-11-1Relevant academic research and scientific papers
The Paal-Knorr reaction revisited. A catalyst and solvent-free synthesis of underivatized and N-substituted pyrroles
Cho, Hyejin,Madden, Richard,Nisanci, Bilal,T?r?k, Bla
, p. 1088 - 1099 (2015/03/04)
A new, modified synthesis of pyrroles is described. The reaction of 2,5-hexandione with a variety of amines yielded the expected pyrrole analogues in excellent yields. The reactions were carried out under the ultimate green conditions excluding both catalyst and solvent applying simple stirring at room temperature. The variety of amines include aqueous ammonium hydroxide for the synthesis of pyrroles with a free NH group, and benzylamines, anilines and phenylene-diamines for the synthesis of several N-derivatized pyrroles. The reaction also occurs efficiently with a variety of 1,4-diketones, although the reaction rates and yields are lower for the diketones that do not possess terminal methyl group(s). This journal is
A new π-system: 1-aryl-2,5-di(2-thienyl)pyrroles
Ogura, Katsuyuki,Yanai, Hiroyuki,Miokawa, Masazumi,Akazome, Motohiro
, p. 8887 - 8891 (2007/10/03)
1-Aryl-2,5-di(2-thienyl)pyrroles and their oligomers have been synthesized as a new π-system. UV-vis absorption spectra, X-ray crystallographic analysis, and cyclic voltammogram showed that the present π-system showed good co-planarity and high ability to
