212499-17-7

Upstream product

• 212492-68-7 methyl 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 347423-83-0 7-benzyloxy-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic acid 
• 212500-90-8 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzoic acid 
• 212500-83-9 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzaldehyde dimethyl acetal 
• 347423-70-5 3-benzyloxy-6-(3,4,5-trimethoxybenzoyl)benzaldehyde 
• 81418-49-7 5-(benzyloxy)-2-bromobenzaldehyde dimethylacetal 
• 5658-49-1 N,N-dimethyl(3,4,5-trimethoxyphenyl)carboxamide 
• 212492-78-9 methyl 2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-7-hydroxy-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylate 
• 212501-44-5 7-benzyloxy-3,4-dihydro-3-hydroxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid 
• 212501-40-1 7-benzyloxy-4-(3,4,5-trimethoxyphenyl)-3-isocoumarincarboxylic acid 

Relevant academic research and scientific papers

Novel, potent, and selective phosphodiesterase 5 inhibitors: Synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives

A novel class of potent and selective phosphodiesterase 5 (PDE5) inhibitors, 4-aryl-1-isoquinolinone derivatives, which have been designed by the comparison of the structure of cGMP and a previously reported 1-arylnaphthalene lignan, was disclosed. Among