212501-59-2

Upstream product

• 212501-54-7 3-benzyloxy-6-(4-bromo-3,5-dimethoxybenzoyl)benzoic acid 

Downstream Products

• 1027416-76-7 4-(4-bromo-3,5-dimethoxy-phenyl)-2-(4-tert-butoxycarbonylamino-phenyl)-1-oxo-7-(pyridin-2-ylmethoxy)-1,2-dihydro-isoquinoline-3-carboxylic acid methyl ester 
• 212498-80-1 methyl 7-benzyloxy-4-(4-bromo-3,5-dimethoxyphenyl)-2-[(4-tert-butoxycarbonylamino)phenyl]-1,2-dihydro-1-oxo-3-isoquinolinecarboxylate 
• 212501-65-0 7-benzyloxy-4-(4-bromo-3,5-dimethoxy-phenyl)-3-hydroxy-1-oxo-isochroman-3-carboxylic acid 

Relevant academic research and scientific papers

Novel, potent, and selective phosphodiesterase 5 inhibitors: Synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives

A novel class of potent and selective phosphodiesterase 5 (PDE5) inhibitors, 4-aryl-1-isoquinolinone derivatives, which have been designed by the comparison of the structure of cGMP and a previously reported 1-arylnaphthalene lignan, was disclosed. Among