212514-56-2

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 217324-56-6 Acetic acid (S)-1-benzyl-3-diazo-2-oxo-propyl ester 
• 84569-94-8 (S)-2-acetoxy-3-phenylpropanoyl chloride 
• 33173-31-8 (S)-3-phenyl-2-acetyloxypropionic acid 

Downstream Products

• 212514-58-4 Acetic acid (S)-1-benzyl-2-oxo-3-(toluene-4-sulfonyl)-pentyl ester 
• 212514-62-0 Acetic acid (S)-3-allyl-1-benzyl-2-oxo-3-(toluene-4-sulfonyl)-hex-5-enyl ester 
• 212514-59-5 Acetic acid (S)-1-benzyl-2-oxo-3-(toluene-4-sulfonyl)-hex-5-enyl ester 
• 212514-61-9 Acetic acid (S)-1-benzyl-2-oxo-4-phenyl-3-(toluene-4-sulfonyl)-butyl ester 

Relevant academic research and scientific papers

A facile synthesis of enantiopure γ-amino- and γ-hydroxy-β- ketosulfones

Enantiopure γ-amino and γ-hydroxy-β-ketosulfones have been synthesized in high yields from α-diazoketones derived from the α-amino and αhydroxy acid chiral pools.

γ-amino-β-ketosulfones as chiral educts: A facile synthesis of enantiopure α-amino ketones

Starting from 'chiral-pool' derived γ-amino-β-ketosulfones, a facile synthesis of enantio-pure α-amino ketones has been developed via an α- alkylation-desulfonation sequence. Extension of this methodology to enantiopure α-acetoxy ketone synthesis, however, have met with limited success.