212519-24-9

Upstream product

• 108-88-3 toluene 

Downstream Products

• 212520-36-0 2-(3-Cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-N-(4-methoxy-phenyl)-acetamide 
• 212519-74-9 5-methyl-7-(p-tolyl)-1,2,4-triazolo[4''',3''':1'',6'']pyrimido[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]-cinnolin-3(2H)-thione 
• 212520-39-3 N-(4-Chloro-phenyl)-2-(3-cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-acetamide 
• 212520-33-7 2-(3-Cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-N-p-tolyl-acetamide 
• 212520-29-1 2-(3-Cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-N-phenyl-acetamide 
• 212519-58-9 (9-Methyl-7-p-tolyl-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthren-11-yl)-hydrazine 
• 212520-17-7 2-(2-Oxo-2-phenyl-ethylsulfanyl)-4-p-tolyl-pyrido[3,2-c]cinnoline-3-carbonitrile 
• 212519-49-8 9-Methyl-7-p-tolyl-10H-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthren-11-one 
• 212519-38-5 9-Methyl-7-p-tolyl-10-oxa-12-thia-5,6,8,13-tetraaza-indeno[1,2-b]phenanthren-11-one 
• 212520-21-3 (3-Cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-acetic acid ethyl ester 
• 212520-45-1 8-Amino-7-p-tolyl-10-thia-5,6,11-triaza-cyclopenta[b]phenanthrene-9-carboxylic acid ethyl ester 
• 212519-54-5 11-Chloro-9-methyl-7-p-tolyl-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthrene 

Relevant academic research and scientific papers

New heterocycles from thienopyridocinnolines

3-Cyano-4-(p-tolyl)pyrido[3,2-c]cinnolin-2(1H) thione 3 was reacted with α-halo ketones, esters, or amides to give the intermediates, S-alkylated products 5b-h, respectively, which underwent intramolecular ring closure reactions with ethanolic sodium ethoxide to give thienopyridocinnolines 6a- h. Pyrimidothienopyridocinnolines 9 and 11 were obtained by treatment of oxazino compound 8 with hydrazine hydrate and ammonium acetate. Treatment of hydrazino derivative 13 with acetylacetone, triethylorthoformate, carbon disulphide, ethyl chloroformate, and acetic anhydride afforded triazolopyrimidothienopyridocinnolines 14-16, 18, and 21, while with nitrous acid the corresponding tetrazolo compound 19 was produced. 3-Cyano-4-(p-tolyl)pyrido[3,2-c]cinnolin-2(1H) thione 3 was reacted with α-halo ketones, esters, or amides to give the intermediates, S-alkylated products 5b-h, respectively, which underwent intramolecular ring closure reactions with ethanolic sodium ethoxide to give thienopyridocinnolines 6a-h. Pyrimidothienopyridocinnolines 9 and 11 were obtained by treatment of oxazino compound 8 with hydrazine hydrate and ammonium acetate. Treatment of hydrazino derivative 13 with acetylacetone, triethylorthoformate, carbon disulphide, ethyl chloroformate, and acetic anhydride afforded triazolopyrimidothienopyridocinnolines 14-16,18, and 21, while with nitrous acid the corresponding tetrazolo compound 19 was produced.