21254-23-9

Basic information

• Product Name: 1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI)
• Synonyms: 1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI);5-AMINO-1-ISOPROPYL-1H-PYRAZOLE-4-CARBONITRILE;5-AMino-1-isopropyl-pyrazole-4-carbonitrile
• CAS NO: 21254-23-9
• Molecular Formula: C7H10N4
• Molecular Weight: 150.1811
• Product Categories: AMINEPRIMARY
• Mol File: 21254-23-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI)(21254-23-9)
• EPA Substance Registry System: 1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI)(21254-23-9)

Safety Data

• Hazardous Substances Data: 21254-23-9(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-4-carbonitrile,5-amino-1-(1-methylethyl)-(9CI) is a chemical compound that consists of a pyrazole ring with a carbonitrile group and an amino group attached. It also contains an isopropyl group, which is a type of alkyl group. This chemical has potential applications in various fields, including pharmaceuticals and agrochemicals. Its structural features and functional groups make it a versatile building block for the synthesis of more complex molecules for use in drug discovery and development, as well as in the production of crop protection products. Research into the potential uses and properties of this compound is ongoing, and it has the potential to contribute to advancements in the fields of medicine and agriculture.

Upstream product

• 2257-52-5 N-isopropylhydrazine 
• 123-06-8 Ethoxymethylenemalononitrile 
• 70629-60-6 isopropylhydrazine hydrochloride 

Downstream Products

• 21254-21-7 1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione 
• 21254-22-8 4,6-dichloro-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 21254-24-0 5-amino-1-(propan-2-yl)-1H-pyrazole-4-carboxamide 

Relevant articles and documents

SUBSTITUTED METHYL PYRAZOLOPYRIMIDINONE AND METHYL IMIDAZOPYRAZINONE COMPOUNDS AS PDE1 INHIBITORS

A chemical entity of Formula (I) or Formula (II): wherein Ra, Rb, Re, and Rf have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in

PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE DERIVATIVES AS PDE9 INHIBITORS

A compound of the general formula (I) wherein R1 is selected from the group consisting of phenyl unsubstituted or substituted with 1 to 3 substituents selected from F, Cl, Br, I, CN, -O-C1-C3-alkyl, fluorinated -O-C1-C3-alkyl, -(CH2)mOH and 5-membered heterocyclic group with 1 or 2 heteroatoms selected from N, O and S; and 6- or 10-membered heteroaryl with 1 to 3 heteroatoms selected from O, N and S; R2 and R3 independently of each other represent H atom or straight or branched C1-C3 alkyl; R4 is selected from the group consisting of 4- to 6- membered cycloalkyl, wherein one of carbon atoms can be replaced by O atom, and which is unsubstituted or substituted with one or two halogen atoms,and straight or branched C1-C4 alkyl; Q represents a bond or C1-C3-alkylene, which can be optionally substituted by one to three C1-C3-alkyls; X is selected from the group consisting of O, NR5, and S(O)p; R5 represents H atom or C1-C3alkyl; m is 1, 2 or 3; p is 0, 1 or 2; and salts thereof, for use as a medicament, in particular for treating cognitive function disorders and neurodegenerative diseases.

AMINO-HETEROCYCLIC COMPOUNDS

The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, A, and n are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.