212554-45-5Relevant academic research and scientific papers
A Facile Method for the Synthesis of 3-Alkyloxindole
Du, Tai-Ping,Zhu, Gang-Guo,Zhou, Jian
, p. 225 - 232 (2012)
Benzylamine in combination with acetic acid was identified as a powerful catalyst for the condensation of oxindole with aldehydes, acetone or cyclic ketones. A variety of 3-alkyloxindoles could be readily prepared in 10 mmol scale via the sequential benzylamine acetate catalyzed condensation of oxindoles with aldehydes (or ketones) and conjugate reduction by NaBH4.
Design, synthesis and cytotoxic activity of spiro(oxindole-3-3'-pyrrolidine) derivatives
Konyar, Dilan,Andac, Cenk A.,Buyukbingol, Erdem
, p. 37 - 45 (2018)
Background: Spiro[pyrrolidine-3,3'-oxindole] compounds are reported to be highly bioactive natural and synthetic products. Initially, spirooxindole alkaloids were isolated from plants of the Apocynaceae and Rubiaceae families, which were found to have a c
Facile synthesis of 3-arylidene-1,3-dihydroindol-2-ones catalyzed by brnsted acidic ionic liquids
Hu, Yi,Kang, Hui,Zeng, Bi-Wen,Huang, He,Wei, Ping
experimental part, p. 263 - 267 (2009/04/11)
A series of 3-arylidene-1,3-dihydroindol-2-one derivatives were conveniently synthesized by the condensation of aromatic aldehydes with 1,3-dihydroindol-2-one using brnsted acidic ionic liquids as dual solvent-catalyst. This method has the advantages of s
