21261-72-3

Usage

Uses

Used in Organic Synthesis:
3-CHLORO-N-(2-CHLOROPHENYL)PROPANAMIDE is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a versatile building block in the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
3-CHLORO-N-(2-CHLOROPHENYL)PROPANAMIDE is used as a key component in the development and production of various pharmaceuticals. Its role in the synthesis of drugs makes it an essential part of the pharmaceutical manufacturing process.
Used in Research and Development:
3-CHLORO-N-(2-CHLOROPHENYL)PROPANAMIDE is used as a research compound for the synthesis of new compounds. It plays a crucial role in advancing scientific knowledge and the development of innovative pharmaceuticals and chemicals.
Safety Precautions:
It is important to handle 3-CHLORO-N-(2-CHLOROPHENYL)PROPANAMIDE with care, as it can be harmful if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken to minimize the risk of exposure to 3-CHLORO-N-(2-CHLOROPHENYL)PROPANAMIDE.

InChI:InChI=1/C9H9Cl2NO/c10-6-5-9(13)12-8-4-2-1-3-7(8)11/h1-4H,5-6H2,(H,12,13)

Upstream product

• 95-51-2 o-chloroaniline 
• 625-36-5 2-chloropropionyl chloride 
• 19565-19-6 3-chloropropionylisothiocyanate 

Downstream Products

• 428829-30-5 3-(3,4-dihydroisoquinolin-2(1H)-yl)-N-(2-chlorophenyl)propanamide 
• 1233488-34-0 C₁₁H₁₁ClN₄OS 

Relevant academic research and scientific papers

Synthesis and biological screening of novel derivatives of 3-(N-substituted carboxamidoethylthio)-(4H)-1,2,4-triazoles

3-Mercapto-(4H)-1,2,4-triazole has been synthesized from 1-formylthiosemicarbazide. Different N-substituted β-chloropropionamides have been prepared by reacting substituted amines with β- chloropropionylchloride. Different Nsubstituted β-chloropropionamides have been condensed with 3-mercapto-(4H)-1,2,4-triazole in basic medium to obtain various 3-(N-substituted carboxamidoethylthio)-(4H)-1,2,4-triazoles. The structure of the synthesized compounds are confirmed by IR, 1H NMR spectra and elemental analysis. All the compounds have been screened for their analgesic, anti-inflammatory and anxiolytic activity.

The synthesis and anticonvulsant activity of some omega-phthalimido-N-phenylacetamide and propionamide derivatives.

In this study, by combining anilide and N', N'-phthaloylglycinamide pharmacophores which are known to produce potent anticonvulsant compounds, sixteen omega-phthalimido-N-phenylacetamide and propionamide derivatives bearing substituents at positions 2 or 2, 6 on N-phenyl ring have been synthesized. The structural confirmation of the title compounds was achieved by interpretation of spectral and analytical data. The anticonvulsant activity of the title compounds was determined against maximal electroshock seizure at 100 mg/kg dose level in mice. The preliminary screening results indicated that omega-phthalimido-N-phenylacetamide and propionamide nuclei have pronounced anticonvulsant activity against maximal electroshock seizure.

Synthesis and anticonvulsant activity of some ω-(1H-1-imidazolyl)-N- phenylalkanoic acid amide derivatives

In this study, 15 ω-(1H-imidazol-1-yl)-N-phenylacetamide, propionamide and butyramide derivatives having methoxyl, methyl, nitro and chloro in ortho position of N-phenyl ring or without any substituent have been realized by two-step synthesis. Their antic

ETHER DERIVATIVES HAVING 5-LIPOXYGENASE INHIBITORY ACTIVITY

The invention concerns ether derivatives of the formula I Q1?X?Ar?Q2 wherein Q1 is an optionally substituted 9-, 10- or 11-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur; X is oxy, thio, sulphinyl or sulphonyl; Ar is optionally substituted phenylene, pyridinediyl, pyrimidinediyl, thiophenediyl, furandiyl, thiazolediyl, oxazoiediyl, thiadiazoiediyl or oxadiazolediyl; and Q2 is selected from the groups of the formulae II and III: wherein R1 is hydrogen, (2-5C)alkanoyl or optionally substituted benzoyl; R2 is (l-4C)alkyl; and R3 is hydrogen or (l-4C)alkyl; or R2 and R3 are linked to form a methylene, vinylene, ethylene or trimethylene group; or a pharmaceutically-acceptable salt thereof; processes for their preparation; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors.