212625-79-1 Usage
Uses
Used in Pharmaceutical Industry:
PYRROLIDINE-2,2,3,3,4,4,5,5-D8 is used as a key building block for the synthesis of various pharmaceutical compounds, specifically MMPIs and APNIs, due to its deuterated nature and structural versatility.
Used in Matrix Metalloproteinase Inhibitors (MMPIs):
PYRROLIDINE-2,2,3,3,4,4,5,5-D8 is utilized as a component in the development of MMPIs, which are essential in the treatment of various diseases, such as cancer, arthritis, and multiple sclerosis. The deuterated pyrrolidine enhances the stability and efficacy of these inhibitors.
Used in Aminopeptidase N Inhibitors (APNIs):
PYRROLIDINE-2,2,3,3,4,4,5,5-D8 is also employed in the synthesis of APNIs, which play a significant role in the regulation of various biological processes, including immune response and blood pressure. The deuterated analogue contributes to the improved performance and selectivity of these inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 212625-79-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,6,2 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 212625-79:
(8*2)+(7*1)+(6*2)+(5*6)+(4*2)+(3*5)+(2*7)+(1*9)=111
111 % 10 = 1
So 212625-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H9N/c1-2-4-5-3-1/h5H,1-4H2/i1D2,2D2,3D2,4D2
212625-79-1Relevant academic research and scientific papers
Ru/C catalyzed cyclization of linear α,ω-diamines to cyclic amines in water
G?dda, Thomas M.,Yu, Xiao-Yan,Miyazawa, Akira
experimental part, p. 1249 - 1253 (2010/03/30)
A facile and convenient way to prepare cyclic amines in water was achieved by the catalyst system composed of Ru/C and Al powder. The α,ω-diaminoalkanes, 1,4-diaminobutane, 1,5-diaminopentane, and 1,6-diamino-heptane were converted to corresponding cyclic amines in good yields. The use of D2O provided a novel route to obtain deuterated cyclic amines in good yields.
