212711-44-9Relevant academic research and scientific papers
Furan ring opening-indole ring closure: Synthesis of furo[2′, 3′:3,4]-cycloheota[1,2-b]indolium chlorides
Butin, Alexander V.,Smirnov, Sergey K.,Stroganova, Tatyana A.
, p. 623 - 628 (2007/10/03)
A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2-b] indolium chlorides is elaborated starting from 2-acetylaminoaryldifurylmethanes or 2-aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclization, intramolecular cyclization, and disproportionation. In this case the furan ring takes part in building up both pyrrole and seven-membered rings. The same salts can be obtained directly from 2-acetylaminobenzaldehydes and 2-methylfuran under similar conditions without isolation of corresponding 2-acetylaminoaryldifurylmethanes.
Polyfuryl(aryl)alkanes and their derivatives. 15. Products from the reduction of 2-nitroaryldifurylmethanes. Synthesis of indole derivatives
Butin,Stroganova,Abaev,Zavodnik
, p. 1393 - 1399 (2007/10/03)
The reduction of 2-nitrophenyldifurylmethane with SnCl2 leads to an indolenyl ketone as a result of intramolecular heterocycloaddition of the intermediately formed nitroso derivative. During the reduction of 2-nitroaryldifurylmethanes in the Zn
