65119-13-3Relevant academic research and scientific papers
New synthesis of 2-nitroaryldifurylmethanes
Tsiunchik,Abaev,Butin
, p. 1476 - 1479 (2005)
A new approach has been developed for the synthesis of 2- nitroaryldifurylmethanes based on the condensation of derivatives of 2-nitrobenzaldehyde and 2-alkylfurans in methylene chloride in the presence of polyphosphoric acid (PPA) silyl ester. The use of
Reduction of bis(5-alkyl-2-furyl)(2-nitroaryl)methane with aqueous titanium trichloride solution
Deng, Wei,Li, Dong-Kun,Tan, Jing-Yi,Xu, Zheng-Yang
supporting information, (2021/09/29)
In this article, we introduces a new method for the synthesis of substituted indole by reductive recyclization of bis(5-alkyl-2-furyl)(2-nitroaryl)methane. Bis(5-alkyl-2-furyl)(2-nitroaryl)methane undergo reduction to provide indole or aniline. In the pro
Anodically Triggered Aldehyde Cation Autocatalysis for Alkylation of Heteroarenes
Liu, Caiyan,Xiao, Zihui,Wu, Shuhua,Shen, Yongli,Yuan, Kedong,Ding, Yi
, p. 1997 - 2001 (2020/02/27)
Alkylation of heteroarenes by using aldehydes is a direct approach to increase molecular complexity, which however often involves the use of stochiometric oxidant, strong acid, and high temperature. This study concerns an energy-efficient electrochemical alkylation of heteroarenes by using aldehydes under mild conditions without mediators. Interestingly, the graphite anode can trigger aldehyde cationic species, which act as the effective autocatalysts to react with a range of heteroarenes to produce the corresponding products with excellent regioselectivity and in high yields. Compared to the traditional electro-synthesis approaches, this electro-triggered reaction provides an electricity-saving and eco-friendly route to high-value chemicals.
Novel synthetic approach to pyrrolo[1,2-b]cinnolines
Abaev, Vladimir T.,Aksenov, Nicolai A.,Chalikidi, Petrakis N.,Demidov, Oleg P.,Gutnov, Andrey V.,Magkoev, Taimuraz T.,Plieva, Anastasia T.,Turiev, Anatolij M.
, (2020/10/02)
[Figure not available: see fulltext.] Straightforward method for the synthesis of pyrrolo[1,2-b]cinnolines starting from 2-nitrobenzaldehydes and 2-methylfurans has been elaborated. The key steps of the process are oxidative furan ring opening with diazon
Intramolecular Pd-catalyzed reductive amination of enolizable sp3-C-H bonds
Ford, Russell L.,Alt, Isabel,Jana, Navendu,Driver, Tom G.
supporting information, p. 8827 - 8831 (2019/10/28)
A palladium-catalyzed reductive cyclization of nitroarenes has been designed to construct sp3-C-NHAr bonds from sp3-C-H bonds by using an enolizable nucleophile to intercept a nitrosoarene intermediate. Exposure of ortho-substituted nitroarenes to 5 mol ?% of Pd(OAc)2 and 10 mol ?% of phenanthroline under 2 atm of CO constructs partially saturated 5-, 6-, or 7-membered N-heterocycles using α-pyridyl carboxylates, malonates, 1,3-dimethylbarbituric acid, 1,3-diones, or difurans as the nucleophile.
Furan ring opening-indole ring closure: SnCl2-induced reductive transformation of difuryl(2-nitroaryl)methanes into 2-(2-acylvinyl)indoles
Uchuskin, Maxim G.,Molodtsova, Natalia V.,Abaev, Vladimir T.,Trushkov, Igor V.,Butin, Alexander V.
experimental part, p. 4252 - 4258 (2012/07/14)
A simple and efficient method for the synthesis of 2-(2-acylvinyl)-3-(5- alkyl-2-furyl)indoles by reductive recyclization of bis(5-alkyl-2-furyl)(2- nitroaryl)methanes is reported. This transformation was carried out by heating the substrates with SnClsu
Furan ring opening - Pyridine ring closure: New route to quinolines under the Bischler-Napieralski reaction conditions
Butin, Alexander V.,Tsiunchik, Fatima A.,Kostyukova, Olga N.,Uchuskin, Maxim G.,Trushkov, Igor V.
scheme or table, p. 2629 - 2638 (2011/10/04)
A new approach to highly functionalized quinolines is proposed. This approach is based on the electrophilic recyclization of 2-[2-(acylamino)benzyl] furans under the Bischler-Napieralski reaction conditions. Georg Thieme Verlag Stuttgart. New York.
Preparation of triaryl- and triheteroarylmethanes under ytterbium triflate catalysis and solvent-free conditions
Genovese, Salvatore,Epifano, Francesco,Pelucchini, Caroline,Curini, Massimo
experimental part, p. 1132 - 1135 (2009/06/18)
Triaryl- and triheteroarylmethanes have been synthesized in very good yield under solvent-free conditions from differently substituted aldehydes and 2-methylfuran or methoxybenzene in the presence of Yb(OTf)3 as catalyst. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.
Synthesis of 2,4-difuryl-4H-3,1-benzothiazines via a furan ring migration reaction
Abaev, Vladimir T.,Tsiunchik, Fatima A.,Gutnov, Andrey V.,Butin, Alexander V.
, p. 475 - 481 (2008/09/19)
(Chemical Equation Presented) A new simple synthetic approach to 2,4-difuryl-4H-3,1-benzothiazines from 2-isothiocyanoaryldifurylmethanes in the presence of acidic catalyst is described. This rearrangement is a new example of furan ring migration reaction
Complexes of titanium(IV) chloride with N-(3,5-R,R′-salicylidene)- 2(3,4)-[bis(5-methyl-2-furyl)methyl]aniline, a novel type of phenoxyimine catalysts for olefin polymerization
Gagieva,Sukhova,Savinov,Tuskaev,Lyssenko,Bravaya,Belokon,Bulychev
, p. 1794 - 1802 (2008/02/01)
New representatives of chelate-type titanium(IV) salicylideneaniline complexes with bis(5-methyl-2-furyl)methyl substituents in the aniline fragment are synthesized. In the presence of poly(methylalumoxane), these complexes catalyze ethylene and propylene polymerization. The effect of the position of substituents in the ligands on the activities of the catalysts is studied. High-molecular-weight linear polyethylene (M w ≈ 172200-300000, M w/M n ≈ 2-3) and high-molecular-weight atactic elastic polypropylene (M w ≈ 1000000, M w/M n ≥ 7.0) are obtained.
