212852-69-2Relevant academic research and scientific papers
Synthesis and antimuscarinic activity of some ether- and thioether-bearing 1,3-dioxolanes and related sulfoxides and sulfones
Malmusi, Luca,Franchini, Silvia,Mucci, Adele,Schenetti, Luisa,Gulini, Ugo,Marucci, Gabriella,Brasili, Livio
, p. 825 - 832 (2007/10/03)
A series of 1,3-dioxolane-based ligands, bearing ether, thioether and related sulfoxide and sulfone functionalities, were synthesised and tested as potential muscarinic antagonists. The compounds display moderate to low affinity for the three receptor sub
