212958-38-8Relevant academic research and scientific papers
Synthesis of geranyl phenyl ethers based on the cytotoxic monoterpenoids from the liverwort genus Trichocolea
Baek, Seung-Hwa,Perry, Nigel B.,Weavers, Rex T.
, p. 1143 - 1145 (1998)
The synthesis of three geranyl ethers, methyl 4-[{(2E)-3,7-dimethyl-5- oxo-2,6-octadienyl}oxy]3-methoxybenzoate (1), methyl 4-[{(2E)-3,7- dimethyl-2,6-octadienyl}oxy]-3-methoxybenzoate (2), and methyl 4-[{(2E)- 3,7-dimethyl-2,6-octadienyl}oxy]-3-hydroxybenzoate (3), previously isolated from New Zealand Trichocolea liverworts, is described. Differing reactivity of the hydroxy groups of methyl protocatachuate toward alkylation and the ability of alkyl groups to migrate from oxygen to an ortho-oxygen in these benzene derivatives are noted.
Phenyl-prenyl-ether derivatives for the treatment of cognitive neurodegenerative or neuronal diseases or disorders
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Page/Page column 26, (2008/06/13)
The present invention is related to a family of phenyl-prenyl-ether derivatives of formula (I), and to their use in the treatment of cognitive, neurodegenerative or neuronal diseases or disorders, such as Alzheimer's disease or Parkinson's Disease. The pr
