2130-26-9Relevant articles and documents
Ruthenium-catalyzed stereo- and chemoselective oxidative coupling of vinyl ketones: efficient access to (E,E)-1,6-dioxo-2,4-dienes
Beeralingappa, Nagabhushana C.,Bhat, Arsheed A.,Dethe, Dattatraya H.,Kumar, Vimlesh,Mishra, Kunj B.,Nirpal, Appasaheb K.,Srivastava, Aparna
supporting information, p. 3063 - 3066 (2022/03/15)
A Ru-catalyzed direct oxidative coupling reaction of vinyl ketones was developed. It offers a straightforward and atom-economical protocol for the synthesis of functionalized (E,E)-1,6-dioxo-2,4-diene derivatives in moderate to good yields with excellent stereo- and chemoselectivities. In addition, the synthetic utility of this method was further demonstrated by its application to the synthesis of bioactive natural products such as (7E,9E)-henicosa-7,9-diene-6,11-dione (sex pheromone), ostopanic acid (plant anticancer agent), JA (anti-tumor agent) and the southern part (C1-C13) of the antibiotic macrolactin-T.
