21303-71-9Relevant academic research and scientific papers
Efficient synthesis of piperazinediones using potassium iodide catalysis in aqueous media
Wen, Yong-Hong,Chen, Xiao-Na,Wen, Hui-Ling,Tang, Xiao-Fang
experimental part, p. 732 - 736 (2012/06/01)
A simple and efficient synthetic approach to 1,4-disubstituted piperazine-2,5-diones was developed. A series of symmetrical 1,4-disubstituted piperazine-2,5-diones was prepared from chloroacetamides using potassium iodide catalysis in acetone/water. The structures of two products were confirmed by single crystal X-ray diffraction analysis.
