213113-05-4

Upstream product

• 128557-02-8 4-bromo-7-methoxy-1,2-dihydronaphthalene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 70157-87-8 N'-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)-4-methylbenzenesulfonohydrazide 

Relevant academic research and scientific papers

Convenient phosphorus tribromide induced syntheses of substituted 1-arylmethylnaphthalenes from 1-tetralone derivatives

A series of 1-arylmethylnaphthalenes 7a-g and 11 have been synthesized conveniently in good yields at room temperature through phosphorus tribromide induced aromatization of 1-aryl-[3,4]-dihydronaphthyl-methanols 6a-g and 10, which were obtained from 1-te

Description anti-mitotic agents which inhibit tubulin polymerization

Methoxy and ethoxy substituted 3-aroyl-2-arylbenzo[b]thiophenes and benzo[b]thiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor cells is also described. Additional aspects described here are certain diaryl ether benzo[b]thiophene derivatives. Also described are particular analogs derived from dihydronaphthalene which have proven particularly effective. Certain new benzofuran analogs are described, as well as certain sulfur oxide benzo[b]thiophene analogs. Important compounds described herein include the first nitrogen-containing derivatives of combretastatin. These include nitro, amino and azide combrdtastatin derivatives.