213115-13-0

Upstream product

• 100-39-0 benzyl bromide 
• 642-78-4 cloxacillin sodium 
• 213115-11-8 (3S,5R,6R)-benzyl 6-[3'-(o-chlorophenyl)-5'-methyl-4'-isoxazolyl]carbonylamino penicillinate 
• 75-31-0 isopropylamine 
• 213115-12-9 (3S,5R,6R)-benzyl 6-[3'-(o-chlorophenyl)-5'-methyl-4'-isoxazolyl]carbonylamino penicillinate sulphoxide 

Downstream Products

• 213115-15-2 (2R,3R)-1-[(1R)-1'-benzyloxycarbonyl-2'-methyl-1',2'-epoxyprop-1'-yl]-2-isopropyl-aminosulphonyl-3-[3'-(o-chlorophenyl)-5'-methylisoxazol-4'yl]carbonylamino-4-oxoazetidine 
• 213115-14-1 (2R,3R)-1-(1'-benzyloxycarbonyl-2'-methylprop-1'-enyl)-2-isopropylaminosulphonyl-3-[3'-(o-chlorophenyl)-5'-methylisoxazol-4'yl]carbonylamino-4-oxoazetidine 
• 446264-41-1 (2S,3R)-1-(1'-benzyloxycarbonyl-2'-methylpropen-1'-yl)-2-acetyloxy-3-[3'-(o-chlorophenyl)-5'-methyl-5'-isoxazol-4'yl]carbonylamino-4-oxoazetidine 
• 446264-42-2 (2S,3R)-1-(1'-benzyloxycarbonyl-2'-methyl-1',2'-epoxypropyl)-2-acetyloxy-3-[3'-(o-chlorophenyl)-5'-methylisoxazol-4'yl]carbonylamino-4-oxoazetidine 

Relevant academic research and scientific papers

Synthesis, structure elucidation and reactivity of novel azetidinone-oxiranes

Oxidation of 2,3-cis-2-sulfonamide-N-butenoate-azetidinone 3 and 2,3-trans-2-acetoxy-N-butenoate-azetidinone 6 led to the formation of azetidinone-oxiranes 5 and 7. Molecular structure of 5, including its absolute configuration, was unambiguously determin

Epoxy-azetidinones, preparation and use thereof

The present invention relates to new epoxy-azetidinones of the general formula I, which are prepared by epoxidizing azetidinones of the general formula II. These compounds are useful intermediates for the prepararion of new potential inhibitors of β-lacta