21316-80-3Relevant academic research and scientific papers
Improved total synthesis of racemic rutamarin
Tong, Ling,Xiong, Ruisheng,Jiang, Hong,Jiang, Xiangrui,Sun, Hongbin,Jiang, Hualiang,Shen, Jingshan
, p. 1697 - 1702 (2011/03/22)
An improved, convenient and cost-effective process, using 2,4-dihydroxybenzaldehyde 2 as starting material for (±)-rutamarin 1, is described. The overall yield of 1 is 44% in eight steps, requiring no chromatographic purification. The Japan Institute of Heterocyclic Chemistry.
Cascade wittig reaction-double claisen and cope rearrangements: One-pot synthesis of diprenylated coumarins gravelliferone, balsamiferone, and 6,8-diprenylumbelliferone
Patre, Rupesh E.,Shet, Jyoti B.,Parameswaran, Perunninakulath S.,Tilve, Santosh G.
scheme or table, p. 6488 - 6490 (2011/02/23)
A cascade Wittig reaction-double Claisen and Cope rearrangements has been employed for a one-pot synthesis of diprenylated coumarins gravelliferone, balsamiferone, and 6,8-diprenylumbelliferone from a common precursor 2,4-diprenyloxybenzaldehyde.
Synthesis of 3-(1,1-Dimethylallyl)xanthyletin, 3-(1,1-Dimethylallyl)-8-(3,3-dimethylallyl)xanthyletin, Gravelliferone and dl-Chalepin
Sharma, R. B.,Kapil, R. S.
, p. 538 - 541 (2007/10/02)
The synthesis of title compounds has been achieved from the key intermediate 3-(1,1-dimethylallyl)-7-hydroxycoumarin (7) which, in turn, is obtained by triple Claisen rearrangement of 7-(3,3-dimethylallyl)oxycoumarin (2) using butyric anhydride as the trapping reagent.
