213182-18-4

Upstream product

• 144446-52-6 tert-Butyl-[(Z)-2-(2,2-dibromo-vinyl)-but-2-enyloxy]-diphenyl-silane 
• 129144-88-3 2-{[(tert-butyldiphenylsilyl)oxy]methyl}-2(E)-butenal 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 213182-17-3 (6E,8Z,10Z)-8-Bromo-10-(tert-butyl-diphenyl-silanyloxymethyl)-dodeca-6,8,10-trien-1-ol 

Downstream Products

• 144446-55-9 (2R,5S,6R,9R)-2-tert-Butyl-6-[(E)-7-(tert-butyl-dimethyl-silanyloxy)-hept-1-enyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-one 
• 144446-45-7 (5S,6R,9R)-3-Benzyloxy-6-[(E)-7-(tert-butyl-dimethyl-silanyloxy)-hept-1-enyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-4-methoxymethoxy-9-methyl-1-oxa-spiro[4.5]deca-3,7-dien-2-one 
• 144446-56-0 (1S,2R,5R)-1-(2-Benzyloxy-acetoxy)-2-[(E)-7-(tert-butyl-dimethyl-silanyloxy)-hept-1-enyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-5-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 213182-19-5 (1S,2R,5R)-2-[(E)-7-(tert-Butyl-dimethyl-silanyloxy)-hept-1-enyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-hydroxy-5-methyl-cyclohex-3-enecarboxylic acid methyl ester 
• 144446-47-9 (6E,8Z,10Z)-1-(tert-butyldimethylsilyloxy)-10-[(tert-butyldiphenylsilyloxy)methyl]dodeca-6,8,10-triene 

Relevant academic research and scientific papers

Studies on the synthesis of chlorothricolide: Diastereo- and enantioselective syntheses of model top-half spirotetronate units

Highly enantio- and diastereoselective syntheses of spirotetronates 9 and 10, corresponding to the top-half fragment of chlorothricolide, are described. Key steps in these syntheses are the Diels-Alder reactions of trienes 11 and 12 with the chiral dienop