213201-62-8

Basic information

• Product Name: 1,3-Propanediol, 1-(4-fluorophenyl)-
• CAS NO: 213201-62-8
• Molecular Formula: C9H11FO2
• Molecular Weight: 170.184
• Mol File: 213201-62-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,3-Propanediol, 1-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediol, 1-(4-fluorophenyl)-(213201-62-8)
• EPA Substance Registry System: 1,3-Propanediol, 1-(4-fluorophenyl)-(213201-62-8)

Safety Data

• Hazardous Substances Data: 213201-62-8(Hazardous Substances Data)

Usage

Derivative of

1,3-propanediol

Substituent

Fluorophenyl on the first carbon atom

Common use

Intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds

Reactivity

Facilitates various chemical reactions

Specific properties

Depend on the context of its application

Potential applications

Fields of medicine and agrochemicals

Upstream product

• 405-99-2 para-fluorostyrene 
• 18511-60-9 4-fluoro-1-cyclopropyl-benzene 
• 63131-29-3 methyl 4-fluorobenzoyl acetate 
• 213201-61-7 C₁₆H₁₇FO₂ 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 70200-12-3 ethyl 3-(4-fluorophenyl)-3-hydroxypropanoate 
• 115168-89-3 3-(4-fluorophenyl)-3-oxopropanal 

Downstream Products

• 926243-84-7 1-(4-fluorophenyl)-3-hydroxypropan-1-one 
• 1621176-40-6 3-(4-fluorophenyl)-3-hydroxypropyl 4-methylbenzenesulfonate 
• 1621176-44-0 1-(4-fluorophenyl)-3-(4,5,6,7-tetrabromo-2H-benzotriazol-2-yl)propan-1-ol 
• 928780-19-2 4-amino-1-{3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-[4-(4-fluoro-phenyl)-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yloxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidin-2-one 

Relevant articles and documents

Lewis Base-Promoted Ring-Opening 1,3-Dioxygenation of Unactivated Cyclopropanes Using a Hypervalent Iodine Reagent

A facile and effective system has been developed for the regio- and chemoselective ring-opening/electrophilic functionalization of cyclopropanes through C?C bond activation by [bis(trifluoroacetoxy)iodo]benzene with the aid of the Lewis basic promoter p-toluenesulfonamide. The p-toluenesulfonamide-promoted system works well for a wide range of cyclopropanes, resulting in the formation of 1,3-diol products in good yields and regioselectivity.

Studies on the chemoenzymatic synthesis of (R)- and (S)-methyl 3-aryl-3-hydroxypropionates: The influence of toluene-pretreatment of lipase preparations on enantioselective transesterifications

Two series (para- and meta-substituted) of racemic methyl esters of 3-aryl-3-hydroxypropionic acid were prepared after which the enantiomers were separated by an enzyme-catalyzed transesterification. Several lipases were investigated as the catalyst. The influence of the enzyme pretreatment, as well as substrate concentration, reaction temperature, stirring manner, and substrate conversion on the stereochemical outcome of the biotransformation process were investigated in detail. The best results were achieved by using solvent-pretreated lipase from Pseudomonas fluorescens or Burkholderia cepacia suspended in toluene, and vinyl acetate as the acetyl group donor.

NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES

Novel 2'-C-methyl nucleoside 5 '-monophosphate and 4'-C-methyl nucleoside 5'- monophosphate derivatives, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral inf