405-99-2

Basic information

• Product Name: 4-Fluorostyrene
• Synonyms: P-FLUOROSTYRENE;1-fluoro-4-ethenylbenzene;1-Fluoro-4-vinylbenzene;para-Fluorostyrene;Styrene, p-fluoro-;4-Fluorostyrene, 97+%;4-Fluorostyrene,98+%;4-Fluorostyrene, stabilized, 97%
• CAS NO: 405-99-2
• Molecular Formula: C₈H₇F
• Molecular Weight: 122.14
• EINECS: 206-975-0
• Product Categories: Styrenes;monomer;Monomers;Polymer Science;Styrene and Functionalized Styrene Monomers;Fluorine series
• Mol File: 405-99-2.mol
• Article Data: 108

Chemical Properties

• Melting Point: -36--33°C
• Boiling Point: 67 °C50 mm Hg(lit.)
• Flash Point: 80 °F
• Appearance: Clear colorless to very slightly yellow/Liquid
• Density: 1.024 g/mL at 25 °C(lit.)
• Vapor Pressure: 6.17mmHg at 25°C
• Refractive Index: n20/D 1.514(lit.)
• Storage Temp.: 2-8°C
• Water Solubility: Insoluble in water.
• BRN: 1634203
• CAS DataBase Reference: 4-Fluorostyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluorostyrene(405-99-2)
• EPA Substance Registry System: 4-Fluorostyrene(405-99-2)

Safety Data

• Hazard Codes: F,Xi
• Statements: 10-36/37/38
• Safety Statements: 23-24/25-37/39-26-16
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 405-99-2(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to very slightly yellow liquid

Uses

4-Fluorostyrene, is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

InChI:InChI=1/C8H7F/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2

Upstream product

• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 7589-27-7 2-(4-Fluorophenyl)ethanol 
• 3020-28-8 (iodomethyl)triphenylphosphonium iodide 
• 459-57-4 4-fluorobenzaldehyde 
• 593-60-2 Vinyl bromide 
• 1765-93-1 4-fluoroboronic acid 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 1415088-90-2 benzyl[1-(4-fluorophenyl)ethyl]selane 
• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 1099728-07-0 1-(4-fluorophenyl)ethyl methanesulfonate 
• 402-63-1 1-(3-fluorophenyl)ethanol 
• 616-91-1 N-acetylcystein 
• 460748-43-0 (E)-2-(4-fluorophenyl)vinylboronic acid 

Downstream Products

• 350-35-6 1-(1,2-dibromoethyl)-4-fluorobenzene 
• 18511-60-9 4-fluoro-1-cyclopropyl-benzene 
• 14331-42-1 6-bromo-3-(4-fluoro-benzyl)-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide 
• 20968-47-2 p-(2,2-Dichlorocyclopropyl)fluorobenzene 
• 37469-90-2 7-(4-fluoro-phenyl)-1,5,6,7-tetrahydro-pyrano[2,3-d]pyrimidine-2,4-dione 
• 64-19-7 acetic acid 
• 109764-64-9 1,10-Dibrom<2.2>paracyclophan-1-en 
• 109764-63-8 1,9-Dibrom<2.2>paracyclophan-1-en 
• 109764-92-3 4'',5'-Bis(4-fluorphenyl)dibenzo<2.2>paracyclophan-1,9-dien-4',5''-dicarbaldehyd 
• 109764-93-4 5',5''-Bis(4-fluorphenyl)dibenzo<2.2>paracyclophan-1,9-dien-4,4''-dicarbaldehyd 
• 109764-88-7 C₃₈H₂₆F₂O₂ 
• 109764-89-8 C₃₈H₂₆F₂O₂ 
• 766-98-3 1-ethynyl-4-fluorobenzene 

Relevant articles and documents

Indene formation upon borane-induced cyclization of arylallenes, 1,1-carboboration, and retro-hydroboration

We herein report the reaction of arylallenes with tris(pentafluorophenyl)borane that yields pentafluorophenyl substituted indenes. The tris(pentafluorophenyl)borane induces the cyclization of the allene and transfers a pentafluorophenyl ring in the course of this reaction. A Hammett plot analysis and DFT computations indicate a 1,1-carboboration to be the C-C bond-forming step.

Electrochemical fluorosulfonylation of styrenes

An environmentally friendly and efficient electrochemical fluorosulfonylation of styrenes has been developed. With the use of sulfonylhydrazides and triethylamine trihydrofluoride, a diverse array of β-fluorosulfones could be readily obtained. This reaction features mild conditions and a broad substrate scope, which could also be conveniently extended to a gram-scale preparation.

Polymerization of Allenes by Using an Iron(II) β-Diketiminate Pre-Catalyst to Generate High Mn Polymers

Herein, we report an iron(II)-catalyzed polymerization of arylallenes. This reaction proceeds rapidly at room temperature in the presence of a hydride co-catalyst to generate polymers of weight up to Mn=189 000 Da. We have determined the polymer structure and chain length for a range of monomers through a combination of NMR, differential scanning calorimetry (DSC) and gel permeation chromatography (GPC) analysis. Mechanistically, we postulate that the co-catalyst does not react to form an iron(II) hydride in situ, but instead the chain growth is proceeding via a reactive Fe(III) species. We have also performed kinetic and isotopic experiments to further our understanding. The formation of a highly unusual 1,3-substituted cyclobutane side-product is also investigated.