213247-66-6Relevant articles and documents
Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics
Dang, Qun,Brown, Brian S.,Liu, Yan,Rydzewski, Robert M.,Robinson, Edward D.,Van Poelje, Paul D.,Reddy, M. Rami,Erion, Mark D.
experimental part, p. 2880 - 2898 (2010/02/28)
Inhibition of FBPase is considered a promising way to reduce hepatic gluconeogenesis and therefore could be a potential approach to treat type 2 diabetes. Herein we report the discovery of a series of purine phosphonic acids as AMP mimics targeting the AM