213247-69-9Relevant articles and documents
Structure-guided design of AMP mimics that inhibit fructose-1,6- bisphosphatase with high affinity and specificity
Erion, Mark D.,Dang, Qun,Reddy, M. Rami,Kasibhatla, Srinivas Rao,Huang, Jingwei,Lipscomb, William N.,Van Poelje, Paul D.
, p. 15480 - 15490 (2008/09/19)
AMP binding sites are commonly used by nature for allosteric regulation of enzymes controlling the production and metabolism of carbohydrates and lipids. Since many of these enzymes represent potential drug targets for metabolic diseases, efforts were ini