213331-31-8Relevant academic research and scientific papers
Synthesis of (+)-anatoxin-a using enyne metathesis
Mori, Miwako,Tomita, Tomohiro,Kita, Yoichi,Kitamura, Tsuyoshi
, p. 4397 - 4399 (2004)
Synthesis of N-tosylanatoxin-a was achieved by metathesis of enyne in cis-substituents on a pyrrolidine derivative. Metathesis reactions of enyne having terminal alkyne using various ruthenium-carbene complexes did not give a good results. However, when t
Further studies on enantioselective synthesis of (+)-anatoxin-a using enyne metathesis: unexpected inversion of chirality via a skeletal rearrangement of 9-azabicyclo[4.2.1]nonene derivative
Tomita, Tomohiro,Kita, Yoichi,Kitamura, Tsuyoshi,Sato, Yoshihiro,Mori, Miwako
, p. 10518 - 10527 (2007/10/03)
The formal total synthesis of (+)-anatoxin-a was accomplished using enyne metathesis as a key step. It is very interesting that (+)-anatoxin-a was synthesized from (S)-pyroglutamic acid via an unusual inversion of chirality, which is rationalized in terms
