213627-34-0Relevant academic research and scientific papers
Synthesis of substituted t-butyl 3-alkyloxindole-3-carboxylates from di-t-butyl (2-nitrophenyl)malonates
Yamai, Yu-Suke,Tanaka, Akio,Yajima, Tatsuo,Ishida, Kyoji,Natsutani, Itaru,Uesato, Shinichi,Nagaoka, Yasuo,Sumiyoshi, Takaaki
, p. 192 - 210 (2019/04/27)
Using a novel tandem reduction-cyclization, we synthesized t-butyl 3-alkyloxindole-3-carboxylates from the di-t-butyl 2-alkyl-2-(2-nitrophenyl)malonate. Introduction of an α-substituent to the di-t-butyl 2-(2-nitrophenyl)-malonates and addition of acid promoted reactivity. This methodology was successfully applied to gram-scale-synthesis of the t-butyl 3-methyloxindole-3-carboxylate 1 and 3-hydroxymethyl-3-methyloxindole 2 without silica gel column chromatography.
Transition metal complexes in organic synthesis. Part 46: Synthesis of 5-arylmethyl-substituted tricarbonyl(1-4-η-cyclohexa-1,3-diene)iron complexes
Knoelker, Hans-Joachim,Graf, Michael,Mangei, Ulrike
, p. 530 - 535 (2011/10/12)
The reaction of tricarbonyl(η5-cyclohexadienylium) iron tetrafluoroborate 3 with the methyl arylacetate 6, the dimethyl arylmalonate 12, and the di-tert-butyl arylmalonate 14 provides regio- and stereoselectively the tricarbonyliron-complexed 5
