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6-Carboxyisatin methyl ester is a chemical compound derived from isatin, an organic compound structurally similar to indole. It is known for its potential therapeutic applications and possesses a carboxylic acid methyl ester functional group. 6-Carboxyisatin methyl es... exhibits a variety of pharmacological activities, including anti-cancer, anti-microbial, and anti-inflammatory properties. It can be synthesized through a carbonylation process, and its structure and properties can be determined using spectroscopic techniques such as NMR and IR spectra. 6-Carboxyisatin methyl es... is typically a solid and should be stored in a cool, dry place away from heat and ignition sources.

213670-35-0

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213670-35-0 Usage

Uses

Used in Pharmaceutical Industry:
6-Carboxyisatin methyl ester is used as a therapeutic agent for its anti-cancer properties. It has the potential to target and inhibit the growth of cancer cells, making it a promising candidate for cancer treatment.
Used in Antimicrobial Applications:
6-Carboxyisatin methyl ester is used as an antimicrobial agent, effective against various microorganisms. Its ability to inhibit microbial growth can be utilized in the development of new antibiotics and antifungal agents.
Used in Anti-inflammatory Applications:
6-Carboxyisatin methyl ester is used as an anti-inflammatory agent, helping to reduce inflammation and alleviate pain. It can be incorporated into medications for the treatment of various inflammatory conditions.
Used in Drug Delivery Systems:
6-Carboxyisatin methyl ester can be used in the development of drug delivery systems to improve the bioavailability and therapeutic outcomes of other drugs. Its chemical properties may allow for the creation of novel carriers and formulations that enhance drug efficacy and reduce side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 213670-35-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,6,7 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 213670-35:
(8*2)+(7*1)+(6*3)+(5*6)+(4*7)+(3*0)+(2*3)+(1*5)=110
110 % 10 = 0
So 213670-35-0 is a valid CAS Registry Number.

213670-35-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-Indole-6-carboxylic acid, 2,3-dihydro-2,3-dioxo-, methyl ester

1.2 Other means of identification

Product number -
Other names methyl 2,3-dioxo-1H-indole-6-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:213670-35-0 SDS

213670-35-0Downstream Products

213670-35-0Relevant academic research and scientific papers

The discovery of potent small molecule activators of human STING

Pryde, David C.,Middya, Sandip,Banerjee, Monali,Shrivastava, Ritesh,Basu, Sourav,Ghosh, Rajib,Yadav, Dharmendra B.,Surya, Arjun

supporting information, (2020/10/09)

The adaptor protein STING plays a major role in innate immune sensing of cytosolic nucleic acids, by triggering a robust interferon response. Despite the importance of this protein as a potential therapeutic target for serious unmet medical conditions inc

HETEROCYCLIC SMALL MOLECULE MODULATORS OF HUMAN STING

-

Page/Page column 117, (2019/01/10)

The present invention relates to compounds of formula (I). The compounds may be used to modulate the Stimulator of Interferon Genes (STING) protein and thereby treat diseases such as cancer and microbial infections. (I)

Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors

Cao, Jingrong,Gao, Huai,Bemis, Guy,Salituro, Francesco,Ledeboer, Mark,Harrington, Edmund,Wilke, Susanne,Taslimi, Paul,Pazhanisamy,Xie, Xiaoling,Jacobs, Marc,Green, Jeremy

scheme or table, p. 2891 - 2895 (2010/01/16)

A series of N-benzylated isatin oximes were developed as inhibitors of the mitogen-activated kinase, JNK3. X-ray crystallographic structures aided in the design and synthesis of novel, selective compounds, that inhibit JNK3, but not p38 MAP kinase and provided key insights into understanding the behavior of gatekeeper residue methionine-146 in determining target selectivity for this series.

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