213686-08-9Relevant academic research and scientific papers
Synthesis of (2S,5S)-5-fluoromethylornithine; a potent inhibitor of ornithine aminotransferase
Ducep,Heintzelmann,Jund,Lesur,Schleimer,Zimmermann
, p. 327 - 335 (1997)
Only one of the four enantiomers of 5-fluoromethylornithine 1 was an irreversible inhibitor of ornithine aminotransferase. The active enantiomer la was synthesized from diaminoadipic acid 2 with a chemical diastereomeric separation and an enantiomeric res
Stereospecific synthesis of cyclic hydrazoacetic acids and meso- diaminodicarboxylic acids
Arakawa, Yasushi,Goto, Takahiro,Kawase, Kazuya,Yoshifuji, Shigeyuki
, p. 674 - 680 (2007/10/03)
The hetero Diels-Alder adducts 6a - d derived from azodibenzoyl and cyclic dienes were oxidized by ruthenium tetroxide and transformed into meso- diaminodicarboxylic acids 12a - d via the new cyclic hydrazoacetic acids 9a - d.
