869-10-3 Usage
Uses
Used in Chemical Synthesis:
Diethyl 2,5-dibromohexanedioate is used as an intermediate in the synthesis of Muconic Acid, a metabolite found in urine in workers with prolonged exposure to Benzene. This application aids in understanding the effects of Benzene exposure on human health.
Used in Polymerization Processes:
Diethyl meso-2,5-dibromoadipate is employed as a difunctional initiator during n-butyl acrylate (n-BuA) polymerization, leading to α,ω-bromo-poly(n-BuA) with a narrow molecular weight distribution. This initiator plays a crucial role in controlling the polymerization process and achieving desired polymer properties.
Used in Atom Transfer Radical Polymerization (ATRP):
Diethyl meso-2,5-dibromoadipate serves as a bifunctional ATRP initiator, enabling the controlled growth of polymer chains with specific molecular weights and architectures. This technique is valuable in the development of advanced polymer materials with tailored properties.
Used in Solution Polymerization:
Diethyl meso-2,5-dibromoadipate acts as an initiator during the solution polymerization of octadecyl ester ether dimer by ATRP. This application contributes to the synthesis of well-defined polymers with potential use in various industries.
Used in Pharmaceutical Synthesis:
Diethyl 2,5-dibromohexanedioate can be used as a pharmaceutical intermediate, playing a role in the development of new drugs and therapeutic agents. Its unique structure allows for further chemical modifications and functionalization.
Used in Laboratory Research and Development:
Diethyl 2,5-dibromohexanedioate is utilized as an organic synthesis intermediate in laboratory research and development processes. It enables chemists to explore new reaction pathways and synthesize novel compounds for various applications.
General Description:
Diethyl meso-2,5-dibromoadipate reacts with N-methylallylamine in the presence of potassium carbonate to yield two diastereomers of diethyl 2-allyl-N-methylpyrrolidine-2,5-dicarboxylate. This reaction showcases the compound's versatility in organic synthesis and its potential use in creating complex molecular structures.
Synthesis
meso-2,5-Dibromo-hexanedioic acid diethyl ester JS-053: Adipic acid (795 g, 3.93 mol) was added in small portions to thionylchloride (980 mL, 5.44 mol) for 2 hours at 65 degC. This suspension was mechanically stirred and heated on an oil bath for an additional 3.5 hours at 70 degC, until the gas evolution was finished. To the UV lamp irradiated (2x 120W) solution was added dropwise bromine (664 mL, 12.48 mol) for 7 hours at 85-95 degC. After finishing of absorption of bromine, the reaction mixture was cooled down, poured into ethanol (4000 mL, 96 %) at -5 degC and mechanically stirred for an additional 1 week at rt. Crystals were filtered off and washed with ethanol (2x 300 mL, 96 %) to afford meso-2,5-dibromo-hexanedioic acid diethyl ester (JS-053, 1343 g, 3.73 mol, yield 95 %, GC 98 %, mp 66 degC/lit.
Check Digit Verification of cas no
The CAS Registry Mumber 869-10-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,6 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 869-10:
(5*8)+(4*6)+(3*9)+(2*1)+(1*0)=93
93 % 10 = 3
So 869-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H16Br2O4/c1-3-9(13)16-8(12)6-5-7(11)10(14)15-4-2/h7-8H,3-6H2,1-2H3/t7-,8+/m0/s1
