213817-03-9

Upstream product

• 213816-77-4 (1R,3R,5R,12R,13S)-(E)-7-benzenesulfonyl-1,5,9-trimethyl-13-(2-methyl-1,3-dioxolan-2-yl)-4-oxatricyclo[10.3.0.0^3,5]pentadeca-8,14-diene 
• 213816-61-6 ethyl (1R,2S,3R,4S)-3-((S)-2,2-dimethyl[1,3]dioxolan-4-yl)-1-methoxymethoxy-2-methyl-5-oxobicyclo[2.2.1]heptane-2-carboxylate 
• 213816-71-8 (E)-{5-benzenesulfonyl-5-[(1R,2R,5S)-2-(benzyloxy)methyl-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-3-cyclopentenyl]-3-methyl-2-pentenyloxy}-tert-butyldimethylsilane 
• 213816-76-3 (2R,3R)-3-[(1R,4S,5R)-5-((E)-5-Benzenesulfonyl-3-methyl-3-pentenyl)-1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-2-cyclopentenylmethyl]-2-methyloxiranylmethyl methanesulfonate 
• 213816-75-2 (E)-4-[(1R,4S,5R)-5-((E)-5-Benzenesulfonyl-3-methyl-pent-3-enyl)-1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-2-enyl]-2-methyl-but-2-enoic acid ethyl ester 
• 213817-02-8 {(2R,3R)-3-[(1R,4S,5R)-5-((E)-5-Benzenesulfonyl-3-methyl-pent-3-enyl)-1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-2-enylmethyl]-2-methyl-oxiranyl}-methanol 
• 213816-63-8 [(1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methoxymethoxy-5-methylbicyclo[2.2.1]hept-2-yloxy]-tert-butyldimethylsilane 
• 213816-74-1 ethyl (E)-4-[(1R,4S,5R)-5-[(E)-5-(tert-butyldimethylsilanyloxy)-3-methyl-3-pentenyl]-1-methyl-4-(2-methyl-1,3-dioxolan-2-yl)-2-cyclopentenyl]-2-methyl-2-butenoate 
• 213817-00-6 (E)-4-[(1R,4S,5R)-5-((E)-5-benzenesulfonyl-3-methyl-3-pentenyl)-1-methyl-4-(2-methyl[1,3]dioxolan-2-yl)-2-cyclopentenyl]-2-methyl-2-buten-1-ol 
• 213816-98-9 (E)-2-Methyl-4-[(1R,4S,5R)-1-methyl-4-(2-methyl-[1,3]dioxolan-2-yl)-5-((E)-3-methyl-5-phenylsulfanyl-pent-3-enyl)-cyclopent-2-enyl]-but-2-enoic acid ethyl ester 
• 213816-69-4 2-((1S,4R,5S)-5-benzenesulfonylmethyl-4-(benzyloxy)methyl-4-methylcyclopent-2-enyl)-2-methyl-1,3-dioxolane 
• 213816-64-9 (1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methoxymethoxy-5-methylbicyclo[2.2.1]hept-2-yl acetate 
• 213816-62-7 ethyl (1R,2S,3R,4S,5S)-5-(tert-butyldimethylsilanyloxy)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-methoxymethoxy-2-methylbicyclo[2.2.1]heptane-2-carboxylate 
• 213816-73-0 methyl [(1R,4S,5R)-5-[(E)-5-((tert-butyldimethylsilanyl)oxy)-3-methyl-3-pentenyl]-1-methyl-4-(2-methyl-1,3-dioxolan-2-yl)-2-cyclopentenyl]acetate 

Downstream Products

• 82799-05-1 3R,4R-epoxy-13-keto-1R,11S-dolabell-7E,12⁽¹⁸⁾-diene 
• 213816-78-5 2-((1S,3R,5R,12S)-(E)-7-benzenesulfonyl-1,5,9-trimethyl-4-oxatricyclo[10.3.0.0^3,5]pentadeca-8,13-dien-13-yl)propan-2-ol 
• 213817-05-1 1-((E)-(1S,3R,5R,12S)-7-Benzenesulfonyl-1,5,9-trimethyl-4-oxa-tricyclo[10.3.0.0^3,5]pentadeca-8,13-dien-13-yl)-ethanone 

Relevant academic research and scientific papers

Total synthesis of the dolabellane marine diterpenoids, claenone, palominol and dolabellatrienone

The synthesis of marine dolabellane diterpenoids claenone, palominol and dolabellatrienone was conducted from D-mannitol. In each case, formation of the bicyclo[2.2.1]heptane derivative by sequential Michael reaction, preparation of the tetrasubstituted c

Total synthesis of dolabellane diterpenoid claenone

Marine dolabellane diterpenoid claenone (1) was synthesized from D- mannitol. This synthesis involves the formation of bicyclo[2.2.1] heptane derivative 4a by sequential Michael reaction, the formation of cyclopentane derivative 9 by retro-aldol reaction