213816-83-2

Upstream product

• 81997-76-4 (S,E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylpropionic acid ethyl ester 
• 100-39-0 benzyl bromide 
• 502442-84-4 Acetic acid (1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-((S)-1,2-dihydroxy-ethyl)-4-hydroxy-5-methyl-bicyclo[2.2.1]hept-2-yl ester 
• 213816-61-6 ethyl (1R,2S,3R,4S)-3-((S)-2,2-dimethyl[1,3]dioxolan-4-yl)-1-methoxymethoxy-2-methyl-5-oxobicyclo[2.2.1]heptane-2-carboxylate 
• 213816-63-8 [(1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methoxymethoxy-5-methylbicyclo[2.2.1]hept-2-yloxy]-tert-butyldimethylsilane 
• 213816-64-9 (1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-methoxymethoxy-5-methylbicyclo[2.2.1]hept-2-yl acetate 
• 213816-62-7 ethyl (1R,2S,3R,4S,5S)-5-(tert-butyldimethylsilanyloxy)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-methoxymethoxy-2-methylbicyclo[2.2.1]heptane-2-carboxylate 
• 213816-81-0 (1S,2S,4R,5R,6R)-5-Benzyloxymethyl-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methoxymethoxy-5-methyl-bicyclo[2.2.1]heptan-2-ol 
• 213816-79-6 (1R,2S,3R,4S,5S)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-1-methoxymethoxy-2-methyl-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 213816-80-9 [(1R,2R,3R,4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methoxymethoxy-2-methyl-bicyclo[2.2.1]hept-2-yl]-methanol 

Downstream Products

• 502442-85-5 Acetic acid (1S,2S,4R,5R,6R)-5-benzyloxymethyl-6-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-5-methyl-bicyclo[2.2.1]hept-2-yl ester 
• 82799-05-1 3R,4R-epoxy-13-keto-1R,11S-dolabell-7E,12⁽¹⁸⁾-diene 
• 213816-86-5 (2R,3R,4S)-4-Acetyl-2-benzyloxymethyl-3-hydroxymethyl-2-methyl-cyclopentanone 
• 213816-92-3 [(1R,2R,5S)-2-Benzyloxymethyl-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-3-enyl]-methanol 
• 213816-88-7 Acetic acid (1R,2R,5S)-5-acetyl-2-benzyloxymethyl-2-methyl-3-oxo-cyclopentylmethyl ester 
• 502442-86-6 (1R,3S,4S,5R,6R)-6-Benzyloxymethyl-5-(tert-butyl-dimethyl-silanyloxymethyl)-6-methyl-bicyclo[2.2.1]heptane-1,3-diol 
• 213816-68-3 ((1R,2R,5S)-2-(benzyloxy)methyl-2-methyl-5-(2-methyl-1,3-dioxolan-2-yl)cyclopent-3-enyl)methyl acetate 
• 213816-90-1 Acetic acid (1R,2R,5S)-2-benzyloxymethyl-3-hydroxy-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-cyclopentylmethyl ester 
• 226718-71-4 (1S,4R,5R,6R)-5-(benzyloxy)methyl-6-((tert-butyldimethylsilanyl)oxymethyl)-4-hydroxy-5-methylbicyclo[2.2.1]heptan-2-one 
• 213816-67-2 ((1R,2R,5S)-2-(benzyloxy)methyl-2-methyl-5-(2-methyl-1,3-dioxolan-2-yl)-3-oxocyclopentyl)methyl acetate 
• 213816-66-1 (2R,3R,4S)-4-acetyl-2-(benzyloxy)methyl-3-((tert-butyldimethylsilanyl)oxymethyl)-2-methylcyclopentanone 
• 213817-05-1 1-((E)-(1S,3R,5R,12S)-7-Benzenesulfonyl-1,5,9-trimethyl-4-oxa-tricyclo[10.3.0.0^3,5]pentadeca-8,13-dien-13-yl)-ethanone 
• 213817-03-9 1-((E)-(1R,3R,5R,12R,13S)-7-Benzenesulfonyl-1,5,9-trimethyl-4-oxa-tricyclo[10.3.0.0^3,5]pentadeca-8,14-dien-13-yl)-ethanone 
• 213816-78-5 2-((1S,3R,5R,12S)-(E)-7-benzenesulfonyl-1,5,9-trimethyl-4-oxatricyclo[10.3.0.0^3,5]pentadeca-8,13-dien-13-yl)propan-2-ol 

Relevant academic research and scientific papers

Total synthesis of the dolabellane marine diterpenoids, claenone, palominol and dolabellatrienone

The synthesis of marine dolabellane diterpenoids claenone, palominol and dolabellatrienone was conducted from D-mannitol. In each case, formation of the bicyclo[2.2.1]heptane derivative by sequential Michael reaction, preparation of the tetrasubstituted c

Total synthesis of dolabellane diterpenoid claenone

Marine dolabellane diterpenoid claenone (1) was synthesized from D- mannitol. This synthesis involves the formation of bicyclo[2.2.1] heptane derivative 4a by sequential Michael reaction, the formation of cyclopentane derivative 9 by retro-aldol reaction