213844-39-4

Basic information

• Product Name: 7-methoxy-2,2-dimethy-3-phenyl-2H-chromene
• Synonyms: 7-methoxy-2,2-dimethy-3-phenyl-2H-chromene
• CAS NO: 213844-39-4
• Molecular Weight: 266.34
• Mol File: 213844-39-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7-methoxy-2,2-dimethy-3-phenyl-2H-chromene(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-2,2-dimethy-3-phenyl-2H-chromene(213844-39-4)
• EPA Substance Registry System: 7-methoxy-2,2-dimethy-3-phenyl-2H-chromene(213844-39-4)

Safety Data

• Hazardous Substances Data: 213844-39-4(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 77-78-1 dimethyl sulfate 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 917-64-6 methyl magnesium iodide 
• 2555-22-8 3-phenyl-7-methoxycoumarin 

Downstream Products

• 78994-24-8 ormeloxifene 

Relevant articles and documents

Synthesis and biological evaluation of trans 6-methoxy-1,1-dimethyl-2- phenyl-3-aryl-2,3-dihydro-1H-inden-4-yloxyalkylamine derivatives against drug susceptible, non-replicating M. tuberculosis H37Rv and clinical multidrug resistant strains

Synthesis of a library of novel trans 6-methoxy-1,1-dimethyl-2-phenyl-3- aryl-2,3-dihydro-1H-inden-4-yloxy alkyl amines and their antimycobacterial activity against drug sensitive and multidrug resistant strains of Mycobacterium tuberculosis have been reported. All the new compounds in the series exhibited MIC between 1.56 and 6.25 μg/ml. Two compounds 1i and 1j with low MIC and low cytotoxicity showed significant reduction in CFU in infected mouse macrophages at 1× MIC concentration. The compound 1i inhibited the growth of M. tuberculosis in mice at 100 mg/kg dose with 1.35 log10 reduction of CFU in lungs tissue and was active against non-replicating Mycobacterium tuberculosis under anaerobic condition.

AN IMPROVED PROCESS FOR THE PREPARATION OF TRANS 3,4- DIARYLCHROMAN AND THEIR DERIVATIVES

The invention describes an improved and advantageous process of preparation of trans 3,4-diarylchroman and similar derivatives there of, useful as anti-fertility, anti-osteoporotic and breast cancer drugs. Condensation of arenes with 2,2- dialkyl-3-aryl c