21394-38-7

Basic information

• Product Name: (2R)-2-amino-2-methyl-3-phenyl-propan-1-ol
• Synonyms: (2R)-2-amino-2-methyl-3-phenyl-propan-1-ol
• CAS NO: 21394-38-7
• Molecular Weight: 165.235
• Mol File: 21394-38-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2R)-2-amino-2-methyl-3-phenyl-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-amino-2-methyl-3-phenyl-propan-1-ol(21394-38-7)
• EPA Substance Registry System: (2R)-2-amino-2-methyl-3-phenyl-propan-1-ol(21394-38-7)

Safety Data

• Hazardous Substances Data: 21394-38-7(Hazardous Substances Data)

Upstream product

• 1268388-07-3 acetic acid 2-methyl-3-phenyl-2-phenylazopropyl ester 
• 17350-84-4 (R)-2-amino-2-methyl-3-phenylpropanoic acid 
• 102-47-6 3,4-Dichlorophenylmethyl chloride 
• 63726-44-3 (2R)-(+)-2-amino-2-methyl-3-phenylpropionamide 
• 22435-99-0 ethyl (R)-2-amino-2-methyl-3-phenylpropanoate 
• 14603-96-4 (R)-(+)-N-Acetyl-α-methyl-phenylalanin 

Downstream Products

• 868286-68-4 tert-butyl (R)-(1-hydroxy-2-methyl-3-phenylpropan-2-yl)carbamate 
• 677005-07-1 tert-butyl ((1R)-1-benzyl-1-methyl-2-oxoethyl)carbamate 
• 868287-50-7 3-(N-methyl-N-(methylsulfonyl)amino)-5-(3-((R)-2-tert-butoxycarbonylamino-1-phenylpropan-2-yl)isoxazol-5-yl)-N-((R)-1-(4-fluorophenyl)ethyl)benzamide 

Relevant articles and documents

CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of Formula (I-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.

Chiral azo compounds: Enantioselective synthesis and transformations into β-amino alcohols and α-amino acids with a quaternary stereocenter

Taking advantage of radical carboaminations producing azo compounds, a new chemo-enzymatic approach to enantiomerically enriched azo alcohols, β-amino alcohols and non-natural (aromatic) amino acids with a quaternary stereocenter is reported.

1,3,5-SUBSTITUTED PHENYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to 1,3,5-phenyl substituted derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.