213984-05-5Relevant articles and documents
Oxidative Intramolecular Phenolic Coupling Reaction Induced by a Hypervalent Iodine(III) Reagent: Leading to Galanthamine-Type Amaryllidaceae Alkaloids
Kita, Yasuyuki,Arisawa, Mitsuhiro,Gyoten, Michiyo,Nakajima, Makiko,Hamada, Ryuji,Tohma, Hirofumi,Takada, Takeshi
, p. 6625 - 6633 (2007/10/03)
By extending our oxidative phenol-coupling reactions using a hypervalent iodine(III) reagent, a versatile synthetic procedure for the galanthamine-type Amaryllidaceae alkaloids was accomplished. The first total synthesis of (±)-sanguinine and the total syntheses of (±)-galanthamine, (±)- narwedine, (±)-lycoramine, and (±)-norgalanthamine were also successfully carried out.