21410-29-7Relevant academic research and scientific papers
D-proline derivatives
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, (2008/06/13)
New compounds have the formula: wherein R, R1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
Regio- and Stereo-Controlled Alkoxyiodination of 1,3-Diene Using Iodine-Cerium(IV) Ammonium Nitrate
Horiuchi, C. Akira,Hosokawa, Haruomi,Kanamori, Miyuki,Muramatsu, Yukiko,Ochiai, Keiko,Takahashi, Eiji
, p. 13 - 14 (2007/10/02)
Reaction of 1,3-cycloalkadienes (cyclopentadiene, cyclohexadiene, and cycloheptadiene) with iodine-cerium(IV) ammonium nitrate in alcohols, gave the corresponding regiospecific trans-2-alkoxy-1-iodo compounds as major products accompanied with 1,4-dialkoxy compounds as by-products.In the case of CH3CN-H2O as solvent, trans-iodohydrins were obtained.Thus the reaction of cyclic and acyclic i671,3-diene derivatives using this synthetic method afforded the 1,2-addition alkoxyiodo compounds preferentially.
VINYL MIGRATION IN THE OXYTHALLATION OF SOME 1,3-DIENES
Murakami, Masashi,Nishida, Shinya
, p. 997 - 1000 (2007/10/02)
The oxythallation of certain 1,3-dienes with thallium (III) nitrate trihydrate in MeOH-CH2Cl2 at 0-20 deg C gave products after vinyl migration .Methyl 1-methylcyclopropyl ketone, obtained in the reaction of 2,3-dimethyl-1,3-butadiene, was presumably derived from a cyclopropylmethyl cation, an intermediate in the vinyl migration.
