21413-70-7

Usage

Uses

Used in Organic Synthesis:
(6E)-6-(hydroxyimino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one is used as a building block in the synthesis of more complex organic molecules. Its unique structure and functional groups allow for a variety of chemical reactions, making it a valuable component in the creation of novel compounds with specific properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (6E)-6-(hydroxyimino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one is used as a starting material for the development of new drugs. Its potential biological activity and reactivity with other chemicals make it a promising candidate for the creation of innovative therapeutic agents.
Used in Chemical Research:
(6E)-6-(hydroxyimino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one is also utilized in chemical research to study its reactivity, stability, and interactions with other molecules. This information can be crucial for understanding its potential applications and for designing new compounds with specific characteristics.

Upstream product

• 826-73-3 1-Benzosuberone 
• 110-46-3 isopentyl nitrite 

Downstream Products

• 53924-47-3 2-phenyl-9,10-dihydro-benzo[5,6]cyclohepta[1,2-d]oxazol-4-one 
• 61727-32-0 2-(3-Cyanopropyl)-benzoesaeure 
• 23445-16-1 cis-6-amino-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol 
• 23699-84-5 2-methyl-4-(1-methyl-piperidin-4-ylidene)-9,10-dihydro-4H-benzo[5,6]cyclohepta[1,2-d]oxazole 
• 28237-14-1 9,10-dihydro-2-methyl-4H-benzo-[5,6]cyclohept[1,2-d]oxazol-4-ol 
• 100447-53-8 methyl-[3-(2-methyl-9,10-dihydro-benzo[5,6]cyclohepta[1,2-d]oxazol-4-ylidene)-propyl]-amine 
• 100447-50-5 methyl-[3-(2-methyl-9,10-dihydro-benzo[5,6]cyclohepta[1,2-d]thiazol-4-ylidene)-propyl]-amine 
• 100447-52-7 [3-(2-ethyl-9,10-dihydro-benzo[5,6]cyclohepta[1,2-d]oxazol-4-ylidene)-propyl]-dimethyl-amine 

Relevant academic research and scientific papers

Chemo- and stereoselective synthesis of benzocycloheptene and 1-benzoxepin derivatives as α-sympathomimetic and anorexigenic agents

The synthesis and pharmacological evaluation of cis- and trans-6-amino-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ols 4a-c and 5a-c and cis- and trans-4-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ols 4d-f and 5d-f were carried out. Chemo- and stereoselective synthesis of 5a-f was achieved by reduction of corresponding α-amino ketones 3a-f with LiAl(t-BuO) 3H. cis-4-Amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol 4d and trans-4-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol 5d exhibited marked anorexigenic activity in mice at a dose of LD50 800 and 500mg/kg and ED50 75 and 55mg/kg, respectively, while the analog cis-2,3-dihydroxy-6-amino-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol 8 showed typical α-sympathomimetic activity.

Benzocycloalkane derivatives and production thereof

Benzocycloalkane derivative of the formula wherein R is a hydrogen atom or a hydrocarbon residue, which may optionally have one or more substituents, Ar is an aromatic group, X is an oxygen or sulfur atom, l is 0 or 1, m is 3 to 6 and n is 0 to 2, wherein the ring A and the group Ar each may optionally have one or more substituents, with the proviso that compounds are excluded, wherein Ar is whereby Rxand Ryare independently selected from alkyl or alkoxy of from one to seven carbon atoms, or its pharmaceutically acceptable salt, which is useful as inhibitors for acyl-CoA : cholesterolacyltransferase.