214153-66-9Relevant academic research and scientific papers
Noncovalent thrombin inhibitors incorporating an imidazolylethynyl p1
Lee, Koo,Jung, Won-Hyuk,Kang, Myunggyun,Lee, Sung-Hack
, p. 2775 - 2778 (2000)
A series of noncovalent tripeptidic thrombin inhibitors incorporating a unidazolylethynyl moiety at P1 was investigated. A number of compounds of this series were highly potent and selective versus trypsin, and several compounds demonstrated good oral absorption in rats (F=58% for compound 19). (C) 2000 Elsevier Science Ltd.
