21419-24-9

Basic information

• Product Name: 3-Amino-2-butanone hydrochloride
• Synonyms: 3-Amino-2-butanone hydrochloride
• CAS NO: 21419-24-9
• Molecular Weight: 123.582
• Mol File: 21419-24-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-Amino-2-butanone hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2-butanone hydrochloride(21419-24-9)
• EPA Substance Registry System: 3-Amino-2-butanone hydrochloride(21419-24-9)

Safety Data

• Hazardous Substances Data: 21419-24-9(Hazardous Substances Data)

Upstream product

• 102872-58-2 2-Ethyl-2,4,5-trimethyl-2,5-dihydro-1H-imidazole 
• 18227-62-8 (+/-)-2-benzamido-3-butanone 
• 2028-33-3 2-(1-methyl-2-oxo-propyl)-isoindole-1,3-dione 
• 6628-81-5 2-acetamido-3-butanone 
• 108-24-7 acetic anhydride 
• 302-72-7 rac-Ala-OH 
• 13058-70-3 3-nitrobutan-2-one 

Downstream Products

• 6016-66-6 3-N-Tritylamino-butanon-⁽²⁾ 
• 1124-11-4 Tetramethylpyrazine 
• 225108-64-5 3-(2,2-dimethoxyethylamino)-2H-1,4-benzoxazin-2-one 
• 225108-63-4 5-chloro-6-(2,6-dichlorophenyl)-3-(1-methyl-2-oxopropylamino)-2H-1,4-oxazin-2-one 

Relevant articles and documents

6-Cycloalkyl-pyrazolopyrimidinones for the Treatment of CNS Disorders

The invention relates to novel 6-Cycloalkyl-pyrazolopyrimidinones according to formula (I). wherein R1 is a 5 or 6 membered aromatic heteroaryl-group, R2 is an optional substituent, D is optionally substituted cyclopentyl, cyclohexyl

Concise synthesis of 1H-pyrazin-2-ones and 2-aminopyrazines

Convenient syntheses of 1H-pyrazin-2-ones and 2-aminopyrazines are described. By coupling Boc-protected amino acids with α-amino ketones or with amino alcohols and subsequent oxidation, 1H-pyrazin-2-ones were obtained. Transformation into the corresponding pyrazine triflates and substitution with primary or secondary amines led to 2-aminopyrazines. Since these syntheses take advantage of the use of readily available starting materials (e.g., amino acids, aminoalcohols and amines) a variety of the entitled structures can be obtained in few, high yielding steps.

Electrolytic Oxidation of Ketones in Ammoniacal Methanol in the Presence of Catalytic Amounts of KI

The indirect electrooxidation of ketones in ammoniacal methanol using iodide ion as a mediator afforded 2,2-dialkyl-2,5-dihydro-1H-imidazoles 3 via an oxidative cyclocoupling of ketimine intermediates formed from ketones and ammonia.The treatment of 3 with dilute HCl gave α-amino ketone hydrochlorides 4 and the parent ketones in good yields.A similar electrooxidation of 3 resulted in the formation of the corresponding 2H-imidazoles 6, which were hydrolyzed to α-diketones and the parent ketones.The same products 6 could also conveniently be obtained by chemical oxidation of 3 with aqueous NaOCl.