214194-52-2

Upstream product

• 14367-67-0 2-methyl-3-phenylpropionic acid 
• 214194-47-5 (R)-N-methoxy-N,2-dimethyl-3-phenylpropanamide 
• 159345-06-9 (2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethyl-3-phenylpropionamide 
• 100-39-0 benzyl bromide 
• 214194-51-1 (R)-4-Methyl-5-phenyl-1-trimethylsilanyl-pent-1-yn-3-one 

Downstream Products

• 214194-54-4 (4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-methyl-6-phenyl-hex-2-yn-1-ol 
• 214194-53-3 tert-Butyl-dimethyl-[(S)-1-((R)-1-methyl-2-phenyl-ethyl)-prop-2-ynyloxy]-silane 

Relevant academic research and scientific papers

Syntheses of the C-1 alkyl side chains of Zaragozic acids A and C

Asymmetric syntheses of the C-1 alkyl side chains of Zaragozic acids A and C from a common chiral precursor 4 are reported. The stereoselective reduction of unsaturated ketones 8 and 10 is the key step of both syntheses.