21422-40-2

Basic information

• Product Name: methyl 2-(1H-indol-2-yl)acetate
• Synonyms: methyl 2-(1H-indol-2-yl)acetate;methyl indole-2-acetate
• CAS NO: 21422-40-2
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21054
• Mol File: 21422-40-2.mol

Chemical Properties

• Melting Point: 68-69 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
• Boiling Point: 341.8±17.0 °C(Predicted)
• Appearance: /
• Density: 1.223±0.06 g/cm3(Predicted)
• PKA: 16.68±0.30(Predicted)
• CAS DataBase Reference: methyl 2-(1H-indol-2-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(1H-indol-2-yl)acetate(21422-40-2)
• EPA Substance Registry System: methyl 2-(1H-indol-2-yl)acetate(21422-40-2)

Safety Data

• Hazardous Substances Data: 21422-40-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Methyl 2-(1H-indol-2-yl)acetate is used as a building block in organic synthesis for the preparation of various indole-based compounds. Its versatile structure allows for the creation of a wide range of chemical entities, making it a valuable component in the development of new molecules.
Used in Pharmaceutical Industry:
As a starting material, methyl 2-(1H-indol-2-yl)acetate is utilized in the synthesis of pharmaceuticals. Its presence in the molecular structure of numerous bioactive compounds makes it an essential precursor in the development of new drugs with potential therapeutic applications.
Used in Agrochemicals:
Methyl 2-(1H-indol-2-yl)acetate also serves as a starting material in the synthesis of agrochemicals. Its role in creating compounds with pesticidal or herbicidal properties contributes to the advancement of agricultural solutions to enhance crop protection and yield.
Used in Medicinal Chemistry Research:
Due to its biological activities, methyl 2-(1H-indol-2-yl)acetate is an important target in medicinal chemistry research. Scientists explore its potential to contribute to the discovery of new therapeutic agents, particularly those that interact with biological systems in meaningful ways.

Upstream product

• 186581-53-3 diazomethane 
• 32588-36-6 indolylacetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 120-72-9 indole 
• 5199-50-8 methyl 2-iodoacetate 
• 18913-35-4 methyl buta-2,3-dienoate 
• 201024-81-9 C,N-diphenylnitrone 

Downstream Products

• 755759-22-9 methyl (3R,7R,8S,8aR)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 755759-16-1 methyl (3R,7R,8S,8aR)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 755759-19-4 methyl (3S,7S,8R,8aS)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 817574-05-3 methyl (3S,7S,8R,8aS)-8-ethyl-α-(2-indolyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine-7-acetate 
• 817574-08-6 (1R,5S,6S,12R)-12-ethyl-2-[(1S)-2-hydroxy-1-phenylethyl]-6-(methoxycarbonyl)-3-oxo-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole 
• 32588-36-6 indolylacetic acid 

Relevant articles and documents

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