214541-53-4

Upstream product

• 850694-99-4 2-hydroxy-5-(1H-indol-3-yl)-2-methylhexan-3-one 
• 120-72-9 indole 
• 487-89-8 Indole-3-carboxaldehyde 
• 74639-50-2 N-benzyloxycarbonyl-indole-3-carbaldehyde 
• 74639-51-3 3-[(2R,3S)-3,4-Dimethyl-5,7-dioxo-2-phenyl-[1,4]oxazepan-(6E)-ylidenemethyl]-indole-1-carboxylic acid benzyl ester 
• 74639-51-3 3-[(2R,3S)-3,4-Dimethyl-5,7-dioxo-2-phenyl-[1,4]oxazepan-(6Z)-ylidenemethyl]-indole-1-carboxylic acid benzyl ester 
• 114515-68-3 ethyl 3-methyl-5H-thiopyrano[4,3,2-cd]indole-2-carboxylate 
• 478916-44-8 2-carboxyl-3-methyl-3,5-dihydro-2H-thiopyrano[4,3,2-cd]indole 
• 63339-68-4 (2R,3S)-2-carboxyl-3-methyl-3,5-dihydro-2H-thiopyrano[4,3,2-cd]indole 
• 81038-38-2 4-iodo-1H-indole 
• 72527-77-6 3-acetyl-4-iodoindole 
• 114495-29-3 ethyl<(3-acetyl-4-indolyl)thio>acetate 

Downstream Products

• 21200-24-8 (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-methylamino-2-oxazolin-4-one 

Relevant academic research and scientific papers

Indole derivatives and its preparation method

The invention relates to a novel antibacterial compound, i.e. an indole derivative, a three-dimensional isomerism or medical salt, solvent compound or aquo-complex as well as a preparation method, a medicine composition containing the compound and an application of the compound in preparing an antibiotic drug.

Highly enantioselective Friedel-Crafts alkylations of pyrroles and indoles with α′-hydroxy enones under Cu(II)-simple bis(oxazoline) catalysis

Remarkably high and regular enantioselectivities are obtained in Friedel-Crafts alkylation reactions involving α-hydroxy enone templates and Cu(II)-bis(oxazoline) complexes as catalysts. The simple elaboration of adducts provides a route to enantioenriche

ASYMMETRIC TOTAL SYNTHESIS OF INDOLMYCIN

An asymmetric total synthesis of indolmycin was achieved via a key intermediate, α-indolmycenic acid ester.The ester was obtained by oxygenation of methyl (S)-3-(3-indolyl)butanoate which was prepared by asymmetric synthesis utilizing (2R,3S)-3,4-dimethyl