214549-16-3

Upstream product

• 214549-14-1 Benzoic acid 2-((4aS,5S,6S,8aS)-6-tert-butoxy-2,2,5-trimethyl-hexahydro-benzo[1,3]dioxin-5-yl)-ethyl ester 
• 98-88-4 benzoyl chloride 
• 155095-85-5 2-((4aS,5S,6S,8aS)-6-tert-Butoxy-2,2,5-trimethyl-hexahydro-benzo[1,3]dioxin-5-yl)-ethanol 

Downstream Products

• 214549-18-5 Benzoic acid 2-[(1S,2S,3S,6S)-6-tert-butoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-1-methyl-cyclohexyl]-ethyl ester 
• 214826-21-8 1-{2-[(1S,2S,3S,6S)-6-tert-Butoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-methoxymethoxy-1-methyl-cyclohexyl]-1-methoxymethoxy-ethyl}-4-(tert-butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-cyclohex-2-enol 
• 214826-22-9 1-[2-((1S,2S,3S,6S)-6-tert-Butoxy-2-hydroxymethyl-3-methoxymethoxy-1-methyl-cyclohexyl)-1-methoxymethoxy-ethyl]-2,6,6-trimethyl-cyclohex-2-ene-1,4-diol 
• 214549-21-0 Benzoic acid 2-[(1S,2S,3S,6S)-6-tert-butoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-methoxymethoxy-1-methyl-cyclohexyl]-ethyl ester 
• 214549-25-4 [(1S,2S,3S,6S)-6-tert-Butoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-methoxymethoxy-1-methyl-cyclohexyl]-acetaldehyde 
• 214549-22-1 2-[(1S,2S,3S,6S)-6-tert-Butoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-methoxymethoxy-1-methyl-cyclohexyl]-ethanol 

Relevant academic research and scientific papers

A concise preparation of an appropriately functionalized B-seco taxane derivative

A successful route to a B-seco taxoid framework of type 2, which may be further manipulated in the expedient synthesis of taxoid ABC-core using standard synthetic procedures is described.

Taxoid C-ring building blocks from Hajos-Parrish ketone. Practical synthesis of an enantiomerically pure taxoid ABC ring system

A synthesis and characterization of conveniently functionalized taxoid C-ring building blocks to be used in an A+C approach is presented. Subsequently, a four-step entry to the tricyclic taxoid ABC skeleton, which allows for a high degree of convergency and is highlighted by a stannylene- mediated coupling to link the left- and right-half moieties, followed by an intramolecular aldol reaction to effect the B-ring closure, is described.