21461-86-9 Usage
Uses
Used in Pharmaceutical Research:
(R)-2-Methyl-5-oxo-tetrahydrofurane-2-carboxylic acid is used as a chiral starting material in pharmaceutical research for [application reason], contributing to the development of innovative drugs and therapies.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-2-Methyl-5-oxo-tetrahydrofurane-2-carboxylic acid is utilized as a building block for the synthesis of other organic compounds, playing a crucial role in creating complex molecular structures.
Used in Agrochemical Development:
(R)-2-Methyl-5-oxo-tetrahydrofurane-2-carboxylic acid is also employed in the development of new agrochemicals, where it serves as a key component in the creation of effective and environmentally friendly products for the agricultural industry.
Safety Precautions:
It is essential to handle (R)-2-Methyl-5-oxo-tetrahydrofurane-2-carboxylic acid with care, as it may pose hazards if not used or stored properly, ensuring safety in the laboratory and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 21461-86-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,6 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21461-86:
(7*2)+(6*1)+(5*4)+(4*6)+(3*1)+(2*8)+(1*6)=89
89 % 10 = 9
So 21461-86-9 is a valid CAS Registry Number.
21461-86-9Relevant academic research and scientific papers
Asymmetric synthesis of 2-alkyl-substituted 2-hydroxyglutaric acid γ-lactones
Paju, Anne,Laos, Marit,J?gi, Artur,P?ri, Malle,J??laid, Raissa,Pehk, T?nis,Kanger, T?nis,Lopp, Margus
, p. 4491 - 4493 (2007/10/03)
3-Alkyl-1,2-cyclopentanediones 1 are transformed into 2-alkyl-2-hydroxyglutaric acid γ-lactones 3 in up to 83% isolated yields and up to 96% ee, affording a simple access to many bioactive compounds, including diacylglycerol lactones (DAG-lactones).
Asymmetric oxidation of 3-alkyl-1,2-cyclopentanediones. Part 2: Oxidative ring cleavage of 3-alkyl-1,2-cyclopentanediones: Synthesis of 2-alkyl-γ-lactone acids
Paju, Anne,Kanger, Tonis,Pehk, Tonis,Lindmaa, Rasmus,Mueuerisepp, Aleksander-Mati,Lopp, Margus
, p. 1565 - 1573 (2007/10/03)
Ti(OiPr)4/diethyl tartrate/tBuOOH system oxidizes 3-alkyl-1,2-cyclopentanediones resulting in hydroxylated ring cleavage products 2-alkyl-γ-lactone acids, in high enantioselectivity (～95% ee) and satisfactory isolated yields (up to 55%).
