214766-79-7Relevant academic research and scientific papers
Direct synthesis of sulfonated dihydroisoquinolinones from: N -allylbenzamide and arylsulfinic acids via TBHP-promoted cascade radical addition and cyclization
Xia, Dong,Li, Yang,Miao, Tao,Li, Pinhua,Wang, Lei
, p. 11559 - 11562 (2016)
A novel synthesis of sulfonated dihydroisoquinolinones via cascade radical addition and cyclization was developed in the presence of tert-butyl hydroperoxide (TBHP). The reactions generated the desired sulfonated dihydroisoquinolinones in good yields from readily available arylsulfinic acids and N-allylbenzamides under metal-free conditions.
A Next-Generation Air-Stable Palladium(I) Dimer Enables Olefin Migration and Selective C?C Coupling in Air
Kundu, Gourab,Rissanen, Kari,Schoenebeck, Franziska,Sperger, Theresa
, p. 21930 - 21934 (2020/10/02)
We report a new air-stable PdI dimer, [Pd(μ-I)(PCy2tBu)]2, which triggers E-selective olefin migration to enamides and styrene derivatives in the presence of multiple functional groups and with complete tolerance of air. The same dimer also triggers extremely rapid C?C coupling (alkylation and arylation) at room temperature in a modular and triply selective fashion of aromatic C?Br, C?OTf/OFs, and C?Cl bonds in poly(pseudo)halogenated arenes, displaying superior activity over previous PdI dimer generations for substrates that bear substituents ortho to C?OTf.
Copper-catalyzed trifluoromethylation and cyclization of aromatic-sulfonyl-group-tethered alkenes for the construction of 1,2-benzothiazinane dioxide type compounds
Dong, Xiang,Sang, Rui,Wang, Qiang,Tang, Xiang-Ying,Shi, Min
supporting information, p. 16910 - 16915 (2014/01/06)
A multi-talented system: An efficient copper-catalyzed tandem trifluoromethylation/annulation of an electron-deficient aromatic ring has been developed. This method provides a powerful and straightforward way to synthesize trifluoromethylated 1,2-benzothiazinane dioxides under mild conditions (see scheme). The mechanism was investigated by a series of kinetic experiments and isotopic labeling studies.
Tandem hydroformylation-hydrazone formation-Fischer indole synthesis: A novel approach to tryptamides
Schmidt, Axel M.,Eilbracht, Peter
, p. 2333 - 2343 (2007/10/03)
A novel one-pot synthesis of indole systems via tandem hydroformylation-hydrazone formation-Fischer indolization starting from allylic amides and aryl hydrazines is described. This tandem procedure directly leads to biologically interesting tryptamides and analogues. The Royal Society of Chemistry 2005.
A new convenient method to obtain pyrroles from tertiary N-allylthioamides
Magedov, Igor V.,Kornienko, Alexander V.,Zotova, Tatyana O.,Drozd, Victor N.
, p. 4619 - 4622 (2007/10/02)
1,2-Disubstituted pyrroles 1 were synthesized from available thioamides 4. Thioamides were initially treated with either alkylating agents or Lewis acids to give salts 5 or complexes 12 which were subsequently reacted with base to yield pyrroles 1.
