214784-06-2Relevant academic research and scientific papers
Inhibition of Glycosidases by Lactam Oximes: Influence of the Aglycon in Disaccharide Analogues
Vonhoff, Stefan,Heightman, Tom D.,Vasella, Andrea
, p. 1710 - 1725 (2007/10/03)
The influence of a substituent at the hydroximo function of the lactam analogue 1 on the inhibition of β- and α-glucosidases is evaluated. In contrast to 1, the O-alkyl oximes 5, 6, 9, and 10 are selective inhibitors of β-glucosidases. Alkylation of the D
