214836-47-2Relevant academic research and scientific papers
Conformationally locked nucleoside analogues based on the bridgehead substituted 7-oxonorbornane and their antiviral properties
Dejmek, Milan,Hrebabecky, Hubert,Dracinsky, Martin,Neyts, Johan,Leyssen, Pieter,Mertlikova-Kaiserova, Helena,Nencka, Radim
, p. 1549 - 1566 (2011)
We report on the preparation of novel 1'-homonucleoside derivatives locked in a West conformation by 1',4'-bridge consisting of annulated benzene or naphthalene ring. The crucial step of the synthesis was Diels-Alder reaction of an appropriate aryne with
