214842-20-3Relevant academic research and scientific papers
Iron-catalyzed oxidative C - H/C - H cross-coupling: An efficient route to α-quaternary α-amino acid derivatives
Li, Kaizhi,Tan, Guangying,Huang, Jingsheng,Song, Feijie,You, Jingsong
, p. 12942 - 12945 (2013)
Fully loaded: A coordinating activation strategy has been developed to furnish α-quaternary α-amino acids through the iron(III)-catalyzed oxidative functionalization of α-C(sp3) - H bonds of α-tertiary α-amino acid esters. The reaction exhibits a broad substrate scope for both α-amino acids and nucleophiles (Nu) as well as good functional-group tolerance (see scheme, DTBP=di-tert-butyl peroxide, DCE=1,2-dichloroethane). Copyright
Convenient preparation of 4-(tetrazol-5-yl)-phenylalanine for use in Fmoc-based solid-phase peptide synthesis
McMurray,Khabashesku,Birtwistle,Wang
, p. 6555 - 6558 (2007/10/03)
To create a novel amino acid incorporating both acidic and aromatic features, trimethyltin azide was used to synthesize L-4-(tetrazol-5-yl)-phenylalanine (Tpa) and the corresponding D,L racemate by [3+2] cycloadditition of azide to the nitrile group of co
Design of benzamidine-type inhibitors of factor Xa
Gabriel, Bernhard,Stubbs, Milton T.,Bergner, Andreas,Hauptmann, J?rg,Bode, Wolfram,Stürzebecher, J?rg,Moroder, Luis
, p. 4240 - 4250 (2007/10/03)
A series of derivatives of rac-benzenesulfonyl-glycyl-phenylalanine or its ethyl ester with a combination of thioamido/amidino or amidino/amidino substituents in the benzene rings was synthesized as potential inhibitors of factor Xa (fXa). Among these, th
