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(3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE, with the molecular formula C6H6BrN2 and IUPAC name N-Methyl-3-bromopyridin-2-amine, is an organobromine compound and a pyridine derivative. It features a six-membered aromatic heterocycle with a bromine atom bonded to a carbon atom. This chemical compound is primarily used for laboratory and research purposes in the field of organic chemistry.

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  • 214977-38-5 Structure
  • Basic information

    1. Product Name: (3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE
    2. Synonyms: (3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE;3-BROMO-2-METHYLAMINOPYRIDINE;3-bromo-N-methylpyridin-2-amine
    3. CAS NO:214977-38-5
    4. Molecular Formula: C6H7BrN2
    5. Molecular Weight: 187.03718
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 214977-38-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: (3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE(214977-38-5)
    11. EPA Substance Registry System: (3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE(214977-38-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 214977-38-5(Hazardous Substances Data)

214977-38-5 Usage

Uses

Used in Organic Chemistry Research:
(3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a valuable building block in the development of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
(3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE is used as a key component in the design and synthesis of new drug molecules. Its presence in the molecular structure can influence the pharmacological properties, such as solubility, stability, and bioavailability, making it a promising candidate for drug discovery and development.
Used in Material Science:
(3-BROMO-PYRIDIN-2-YL)-METHYL-AMINE is used as a functional group in the creation of new materials with specific properties. Its incorporation into polymers or other materials can lead to enhanced characteristics, such as improved thermal stability, conductivity, or mechanical strength, depending on the application.

Check Digit Verification of cas no

The CAS Registry Mumber 214977-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,9,7 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 214977-38:
(8*2)+(7*1)+(6*4)+(5*9)+(4*7)+(3*7)+(2*3)+(1*8)=155
155 % 10 = 5
So 214977-38-5 is a valid CAS Registry Number.

214977-38-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-bromo-N-methylpyridin-2-amine

1.2 Other means of identification

Product number -
Other names 3-bromo-N-methyl-2-pyridinamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:214977-38-5 SDS

214977-38-5Relevant articles and documents

Hetarynic synthesis and chemical transformation of dihydrodipyridopyrazines

Blanchard, Stéphanie,Rodriguez, Ivan,Kuehm-Caubère, Catherine,Renard, Pierre,Pfeiffer, Bruno,Guillaumet, Gérald,Caubère, Paul

, p. 3513 - 3524 (2002)

Unprecedented dihydrodipyridopyrazines were easily obtained by hetarynic dimerization of 2-alkylamino-3-halogenopyridines in the presence of the complex base NaNH2-tBuONa. Derivatizations of the new heterocycles are described. The anticancer ac

Efficient synthesis of 3-bromo-2-[(N-substituted)amino]pyridines and their hetarynic cyclization

Grig-Alexa, Irina-Claudia,Finaru, Adriana-Luminita,Ivan, Lucia,Caubère, Paul,Guillaumet, Gérald

, p. 619 - 628 (2006)

A variety of 3-bromo-2-[(N-substituted)amino]pyridines were obtained via two convenient methods and were used in the hetarynic synthesis of the corresponding N-substituted dihydro-dipyridopyrazines. Georg Thieme Verlag Stuttgart.

Towards New Tricyclic Motifs: Intramolecular C–H Arylation as the Key Step in a Formal [3+3] Cyclocondensation Strategy

Vrijdag, Johannes L.,De Ruysscher, Dries,De Borggraeve, Wim M.

, p. 1465 - 1474 (2017/04/01)

Tricyclic scaffolds structurally related to the well-known benzodiazepine class of drugs show diverse biological activities strikingly different from those of their benzodiazepine counterparts. Interested by this scaffold-hopping perspective, we previousl

Reductive cyclization of halo-ketones to form 3-hydroxy-2-oxindoles via palladium catalyzed hydrogenation: a hydrogen-mediated Grignard addition

Shin, Inji,Ramgren, Stephen D.,Krische, Michael J.

supporting information, p. 5776 - 5780 (2015/08/03)

Abstract The reductive cyclization of N-oxoacyl ortho-bromoanilides to form 3-hydroxy-2-oxindoles under the conditions of palladium catalyzed hydrogenation is described. This work may be viewed as a prelude to intermolecular hydrogen-mediated Grignard-typ

Synthesis of nitro N,N′-dipyridinylamines via oxidative nucleophilic substitution of hydrogen

Patriciu, Oana-Irina,Pillard, Christelle,Finaru, Adriana-Luminita,Sandulescu, Ioan,Guillaumet, Gerald

, p. 3868 - 3876 (2008/09/17)

The amination of 3-nitropyridines with aromatic amides generated from various aminopyridine derivatives proceeded unexpectedly in the position para to the nitro group, giving the oxidative nucleophilic substitution of hydrogen (ONSH) derived compounds. After optimization, this reaction allowed easy access to interesting 3-nitro-substituted N,N′-dipyridinylamines. Georg Thieme Verlag Stuttgart.

5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds

-

, (2008/06/13)

A compound selected from those of formula (I): wherein: X represents N, C or CH, Y represents N when X represents C or CH, or Y represents C or CH when X represents N, R1 represents an optionally substituted alkyl, R2 and R3, which may be identical or different, represent Z or W, as defined in the description, their isomers and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.

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