215163-68-1

Basic information

• Product Name: (2R,3S)-4-benzyloxy-3-hydroxy-2-monobenzylsuccinamidyl-butanoic acid
• Synonyms: (2R,3S)-4-benzyloxy-3-hydroxy-2-monobenzylsuccinamidyl-butanoic acid
• CAS NO: 215163-68-1
• Molecular Weight: 415.443
• Mol File: 215163-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-4-benzyloxy-3-hydroxy-2-monobenzylsuccinamidyl-butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-4-benzyloxy-3-hydroxy-2-monobenzylsuccinamidyl-butanoic acid(215163-68-1)
• EPA Substance Registry System: (2R,3S)-4-benzyloxy-3-hydroxy-2-monobenzylsuccinamidyl-butanoic acid(215163-68-1)

Safety Data

• Hazardous Substances Data: 215163-68-1(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 103-40-2 succinic acid monobenzyl ester 
• 21768-33-2 (2S,3R)-2-amino-4-(benzyloxy)-3-hydroxybutanoic acid 
• 117679-91-1 1-O-benzyl 4-O-(2,-5-dioxopyrrolidin-1-yl) butanedioate 

Downstream Products

• 236744-34-6 (2S,3S)-3-Allyloxy-2-[(2S,3R)-4-benzyloxy-2-(3-benzyloxycarbonyl-propionylamino)-3-hydroxy-butyrylamino]-4-((2S,3R,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yl)-butyric acid ethyl ester 
• 215163-56-7 N-((1S,2R)-1-{Benzyl-[1-(methoxycarbonylmethyl-carbamoyl)-2-((2S,3R,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yl)-ethyl]-carbamoyl}-3-benzyloxy-2-hydroxy-propyl)-succinamic acid benzyl ester 

Relevant articles and documents

Synthesis of sialyl Lewis X mimetics: Use of O-α-fucosyl-(1R, 2R)-2-aminocyclohexanol as core structure

Six glycopeptides containing O-α-fucosyl-(1R, 2R)-2-aminocyclohexanol were designed and prepared as sialyl Lewis X mimetics. Compounds 2 and 6 showed better binding affinities than SLe(X) (IC50 = 0.5 mM) to E-selectin with IC50 values of 0.4 and 0.2 mM respectively.